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Getting under your skin: Molecular research builds new understanding of skin regeneration As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal. Skin’s barrier function gives it the unique ability to fight winter woes and retain water for our bodies. The outer layer of the skin, the epidermis, is constantly turning over to replace dead or damaged cells, creating new cells to reinforce the barrier function and heal damage. The gene regulatory mechanisms that control epidermis turnover remain incompletely understood. ....