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Researchers identify novel approach to repair the human heart


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Maywood, Ill. - May 19, 2021 - A team of scientists from Loyola University Chicago s Stritch School of Medicine have discovered a critical component for renewing the heart s molecular motor, which breaks down in heart failure.
Approximately 6.2 million Americans have heart failure, an often fatal condition characterized by the heart s inability to pump enough blood and oxygen throughout the body. This discovery could represent a novel approach to repair the heart.
Their findings, published in the May 19 issue of
Nature Communications, show how a protein called BAG3 helps replace worn-out components of the cardiac sarcomere. The sarcomere is a microscopic structure inside every heart muscle cell that causes it to contract. All the cells then work together to make the heart pump blood around the body. ....

United States , Monte Willis , Meharvan Singh , Jonathana Kirk , Christine Moravec , Shubham Dubey , Edith Perez , Thomas Martin , Valerie Myers , Praveen Dubey , Indiana University , Nature Communications , American Heart Association , National Institutes Of Health , Department Of Cell , Temple University Philadelphia , Loyola University Chicago Stritch School Of Medicine , Loyola University Chicago , Stritch School , Senior Investigator Jonathan , Molecular Physiology , Bart Feldman , Temple University , Cleveland Clinic , National Institutes , American Heart ,

Scientists discover key component to repair the molecular motor of human heart


Scientists discover key component to repair the molecular motor of human heart
A team of scientists from Loyola University Chicago s Stritch School of Medicine have discovered a critical component for renewing the heart s molecular motor, which breaks down in heart failure.
Approximately 6.2 million Americans have heart failure, an often fatal condition characterized by the heart s inability to pump enough blood and oxygen throughout the body. This discovery could represent a novel approach to repair the heart.
Their findings, published in the May 19 issue of
Nature Communications, show how a protein called BAG3 helps replace worn-out components of the cardiac sarcomere. The sarcomere is a microscopic structure inside every heart muscle cell that causes it to contract. All the cells then work together to make the heart pump blood around the body. ....

United States , Thomas Martin , Meharvan Singh , Jonathana Kirk , Emily Henderson , Loyola University , Nature Communications , Loyola University Chicago Stritch School Of Medicine , Department Of Cell , Stritch School Of Medicine , Loyola University Chicago , Stritch School , Senior Investigator Jonathan , Associate Professor , Study Senior Investigator , Molecular Physiology , Heart Failure , ஒன்றுபட்டது மாநிலங்களில் , தாமஸ் மார்டின் , எமிலி ஹென்டர்சன் , லயோலா பல்கலைக்கழகம் , இயற்கை தகவல்தொடர்புகள் , லயோலா பல்கலைக்கழகம் சிகாகோ தையல் பள்ளி ஆஃப் மருந்து , துறை ஆஃப் செல் , தையல் பள்ளி ஆஃப் மருந்து , லயோலா பல்கலைக்கழகம் சிகாகோ ,