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Novel altruistic stem cell defense mechanism may be targeted to develop new COVID-19 vaccines


Novel altruistic stem cell defense mechanism may be targeted to develop new COVID-19 vaccines
The SARS-CoV-2 virus that causes COVID-19 may have the ability to reactivate dormant tuberculosis (TB). In a novel study scientists report in
The American Journal of Pathology that infection with a specific coronavirus strain reactivated dormant Mycobacterium tuberculosis (MTB) in mice. This knowledge may help to develop new vaccines for COVID-19 and avoid a potential global tuberculosis epidemic.
The COVID-19 pandemic caused by the SARS-CoV-2 virus demonstrates the ability of an emerging virus to affect masses and strain and disrupt the workings of modern healthcare systems around the world. A significant number of infected COVID-19 individuals have recovered. However, a possible host defense or antiviral mechanism against the virus is yet to be identified. There are concerns that in the long-term, the virus might activate dormant bacterial infections such as TB in select in ....

United States , Upakarvada Vedic , Lekhika Pathak , Bikul Das , Herman Yeger , Krishna Ram Das , Emily Henderson , Kavikrishna Foundation , Department Of Pediatric Laboratory Medicine , Kavikrishna Laboratory , University Of Massachusetts , Department Of Stem Cell , Indian Institute Of Technology , Kavikrishna Lab , Thoreau Lab For Global Health , American Journal , Lead Investigator , Stem Cell , Infectious Diseases , Guwahati Biotech Park , Indian Institute , Thoreau Lab , Global Health , Indian Vedantic Philosophical , Vedic Jiva Upakarvada , Pediatric Laboratory Medicine ,

Researchers make 'bombshell' discovery of an entirely new kind of biomolecule


Date Time
Researchers make ‘bombshell’ discovery of an entirely new kind of biomolecule
A newfound biomolecule, consisting of RNA modified by sugars, could be present in all forms of life and might contribute to autoimmune disease.
By Holly Alyssa MacCormick
Stanford researchers have discovered a new kind of biomolecule that could play a significant role in the biology of all living things.
The novel biomolecule, dubbed glycoRNA, is a small ribbon of ribonucleic acid (RNA) with sugar molecules, called glycans, dangling from it. Up until now, the only kinds of similarly sugar-decorated biomolecules known to science were fats (lipids) and proteins. These glycolipids and glycoproteins appear ubiquitously in and on animal, plant and microbial cells, contributing to a wide range of processes essential for life. ....

United States , Stacy Malaker , Benson George , Kayvon Pedram , Holly Alyssa Maccormick , Alex Johnson , Karim Majzoub , Jan Carette , Stanford Bio , Howard Chang , Ryan Flynn , Carolyn Bertozzi , Stanford School Of Humanities , National Cancer Institute , National Science Foundation , Department Of Stem Cell , Damon Runyon Cancer Research , Dk Ludwig Professor Of Cancer Research , Cancer Research Of The United States , Maternal Child Health Research Institute , National Institute , Stanford Wu Tsai Neurosciences Institute , Yale University , Stanford Chemistry Biology Interface Predoctoral Training Program , National Institutes Of Health , Medicine For Human Health ,