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Living on knife's edge- The New Indian Express


Living on knife’s edge
On World Haemophilia Day, experts highlight the need for awareness and early diagnosis. They also urge patients to take the Covid vaccine on a priority basis
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HYDERABAD :  K Aravind Nikhil’s life is an embodiment of the phrase ‘living on a knife-edge’. Aravind is a regular 25-year-old cheerful, IT professional with dreams of a good life. Until he says one would never know that he suffers from haemophilia, an incurable congenital genetic bleeding disorder. 
Aravind’s life is dotted with many ‘near misses’. Since the age of six months, he has suffered from spontaneous internal bleeds, i.e., bleeds without any injury to joints, muscles, hands or other parts.  ....

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BLINCYTO® Demonstrated Significantly Prolonged Event-Free Survival Compared With Consolidation Chemotherapy In Pediatric Patients With Relapsed Acute Lymphoblastic Leukemia


Amgen today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO ® compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia were published in The Journal of the American Medical Association . 1 BLINCYTO …
Amgen (NASDAQ:AMGN) today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO ® (blinatumomab) compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia (B-ALL) were published in The Journal of the American Medical Association (JAMA) . 1 ....

Puerto Rico , United States , New Zealand , Trish Rowland , Jessica Akopyan , Franco Locatelli , Davidm Reese , National Cancer Institute , Operations Center Grant , European Union , University Of Rome , Development Agreement , National Clinical Trials Network , National Institutes Of Health , Children Oncology Group , Administration Guidelines , Drug Administration , Data Monitoring Committee , Beigene Ltd , Journal Of The American Medical Association , Exchange Commission , Department Of Pediatric Hematology , American Medical Association , Pediatric Hematology , Bambino Ges , Oncology Group ,

BLINCYTO® (Blinatumomab) Demonstrated Significantly Prolonged Event-Free Survival Compared With Consolidation Chemotherapy In Pediatric Patients With Relapsed Acute Lymphoblastic Leukemia


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THOUSAND OAKS, Calif., March 2, 2021 /PRNewswire/ Amgen (NASDAQ:AMGN) today announced that data from a multicenter, randomized Phase 3 study evaluating the efficacy, safety and tolerability of BLINCYTO
® (blinatumomab) compared with consolidation chemotherapy before allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric patients with high-risk first-relapse B-cell precursor acute lymphoblastic leukemia (B-ALL) were published in
The Journal of the American Medical Association (JAMA).
1
BLINCYTO demonstrated significantly prolonged event-free survival (events were defined by relapse, death, second malignancy, or failure to achieve complete remission) compared with chemotherapy. After a median of 22.4 months follow-up, 69% of patients treated with BLINCYTO were alive and event-free compared with 43% of patients treated with chemotherapy. Additionally, following treatment with BLINCYTO, 93% of patien ....

Puerto Rico , United States , New Zealand , Trish Rowland , Jessica Akopyan , Franco Locatelli , Davidm Reese , National Cancer Institute , Operations Center Grant , European Union , University Of Rome , Development Agreement , National Clinical Trials Network , National Institutes Of Health , Children Oncology Group , Administration Guidelines , Drug Administration , Data Monitoring Committee , Beigene Ltd , Journal Of The American Medical Association , Exchange Commission , Department Of Pediatric Hematology , American Medical Association , Pediatric Hematology , Bambino Ges , Oncology Group ,