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Experts debate the effectiveness of a single dose versus a double dose of the COVID-19 vaccine Johnson & Johnson s one-shot vaccine shows promise George Frey/Getty Images SALT LAKE CITY, UT - APRIL 26: In this photo illustration sterile water is prepared for a one dose bottle of measles, mumps and rubella virus vaccine, made by MERCK, at the Salt Lake County Health Department on April 26, 2019 in Salt Lake City, Utah. (Photo Illustration by George Frey/Getty Images) and last updated 2021-01-15 13:18:48-05 DENVER â The vaccineâs arrival in Colorado last month was rightly celebrated by the governor and others. But the rollout here and in other states has been somewhat chaotic, messy and frustrating â especially for higher-risk Coloradans trying to get the vaccine. ....