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Cell viability require that a variety of functions at the cell membrane are maintained properly. P-type ATPases translocate substrates across the membrane, and they have evolved into different types taking care of specific substrates within a diverse range. Now, key structural aspects have been described on how two different types of P-type ATPases a Ca2+ transporting Ca2+-ATPase and a lipid transporting P4-ATPase - have adapted to different substrates and physical environments. ....

Josepha Lyons , Jacob Lauwring Andersen , Thomas Boesen , Milena Timcenko , Sara Basse Hansen , Caroline Neumann , Mateusz Dyla , Magnus Kj , Esben Meldgaard Hoegh Quistgaard , Aarhus University , Postdoc Milena Timcenko , Professor Poul Nissen , Molecular Biology , Crystal Structure , Pump Primed , Magnus Kjaergaard , Guillaume Lenoir , Poul Nissen , Cell Biology , Molecular Biology , தாமஸ் போஸன் , மேக்னஸ் க்ஜ் , ஆர்ஹஸ் பல்கலைக்கழகம் , மூலக்கூறு உயிரியல் , படிக அமைப்பு ,