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Brain Scans Reveal New Autism Subtypes


Brain Scans Reveal New Autism Subtypes
by Pooja Shete on 
December 23, 2020 at 10:25 PM
The research conducted at the UC Davis Mind Institute is published in the journal
Biological Psychiatry.
The research was based on the brain scans taken over many years as part of the Girls with Autism, Imaging of Neurodevelopment (GAIN) and Autism Phenome Project (APP) studies that showed the importance of longitudinal studies that follow the same children from diagnosis into adolescence.
Big Brains
For the first study, the researchers used magnetic resonance imaging (MRI) to track the size of brain (volume) in 135 children without autism and 294 children with autism between the ages of 3 and 12. In children with autism, it was found that larger brain size relative to height- or disproportionate megalencephaly. It is a subtype linked with higher rates of intellectual disability and poorer overall prognosis. ....

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Scientists find clues about autism subtypes


Scientists find clues about autism subtypes
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Researchers tracked brain growth and structure in hundreds of children from age 3 to age 12. UC Davis Health/Courtesy photo
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UC Davis MIND Institute researchers tracked brain changes in children over many years using MRI scans
SACRAMENTO Two studies at the UC Davis MIND Institute provide clues about possible types of autism linked to brain structure, including size and white-matter growth.
The research is based on brain scans taken over many years as part of the Autism Phenome Project  and Girls with Autism, Imaging of Neurodevelopment studies. It shows the value of longitudinal studies that follow the same children from diagnosis into adolescence. ....

United States , Sally Ozonoff , David Amaral , Sallyj Rogers , Joshua Lee , Einat Waizbard Bartov , Joshuak Lee , Derek Sayre Andrews , Christine Wu Nordahl , Danielle Jenine Harvey , National Institute Of Mental Health , Autism Center , Institute Autism Research Training Program , Developmental Disabilities Research Center , Autism Phenome Project , Biological Psychiatry , Cerebral Growth Across Childhood , Autism Spectrum , Marjorie Solomon , Derek Sayre , National Institute , Mental Health , Institute Intellectual , Longitudinal Study , White Matter Development , Autism Severity Across Early ,

Studies provide clues about possible types of autism linked to brain structure


Studies provide clues about possible types of autism linked to brain structure
Two groundbreaking studies at the UC Davis MIND Institute provide clues about possible types of autism linked to brain structure, including size and white matter growth.
The research is based on brain scans taken over many years as part of the Autism Phenome Project (APP) and Girls with Autism, Imaging of Neurodevelopment (GAIN) studies. It shows the value of longitudinal studies that follow the same children from diagnosis into adolescence.
There is no other single site data set like ours anywhere, said Christine Wu Nordahl, associate professor in the Department of Psychiatry and Behavioral Sciences, MIND Institute faculty member and co-senior author on both papers. In one of the studies we have over 1,000 MRI scans from 400 kids, which is unheard of. It s been 15 years of work to get here. ....

David Amaral , Joshua Lee , Derek Sayre Andrews , Christine Wu Nordahl , Emily Henderson , Behavioral Sciences , Department Of Psychiatry , Autism Phenome Project , Biological Psychiatry , Study Lead Author , Postdoctoral Scholar , டேவிட் அமரல் , ஜோஷுவா லீ , டெரெக் ஸேர் ஆண்ட்ரூஸ் , எமிலி ஹென்டர்சன் , நடத்தை அறிவியல் , துறை ஆஃப் மனநல மருத்துவம் , உயிரியல் மனநல மருத்துவம் , படிப்பு வழி நடத்து நூலாசிரியர் , போஸ்ட்‌டாக்டொரல் அறிஞர் ,

Big brains and white matter: New clues about autism subtypes


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VIDEO: Two new longitudinal studies from the UC Davis MIND Institute reveal clues about autism subtypes.
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Credit: UC Davis Health
Two groundbreaking studies at the UC Davis MIND Institute provide clues about possible types of autism linked to brain structure, including size and white matter growth.
The research is based on brain scans taken over many years as part of the Autism Phenome Project (APP) and Girls with Autism, Imaging of Neurodevelopment (GAIN) studies. It shows the value of longitudinal studies that follow the same children from diagnosis into adolescence.
There is no other single site data set like ours anywhere, said Christine Wu Nordahl, associate professor in the Department of Psychiatry and Behavioral Sciences, MIND Institute faculty member and co-senior author on both papers. In one of the studies we have over 1,000 MRI scans from 400 kids, which is unheard of. It s been 15 years of work to get here. ....

Sally Ozonoff , David Amaral , Sallyj Rogers , Joshua Lee , Einat Waizbard Bartov , Joshuak Lee , Derek Sayre Andrews , Christine Wu Nordahl , Danielle Jenine Harvey , National Institute Of Mental Health , Autism Center , Institute Autism Research Training Program , Developmental Disabilities Research Center , Behavioral Sciences , Department Of Psychiatry , Autism Phenome Project , Biological Psychiatry , Cerebral Growth Across Childhood , Autism Spectrum , Marjorie Solomon , Derek Sayre , National Institute , Mental Health , Institute Intellectual , Longitudinal Study , White Matter Development ,