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Can an immune cell fix 'de-age' the brain?

Researchers have identified a key factor in mental aging.
They’ve also shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.
Certain cells of our immune system become increasingly irascible as we grow older. Instead of stamping out embers, they stoke the flames of chronic inflammation.
Biologists have long theorized that reducing this inflammation could slow the aging process and delay the onset of age-associated conditions, such as heart disease, Alzheimer’s disease, cancer, and frailty, and perhaps even forestall the gradual loss of mental acuity that happens to nearly everyone. ....

United States , Katrin Andreasson , Geraldj Lieberman , Taube Family Foundation , Stanford Innovation Fund , American Heart Association , Burroughs Wellcome Fund , Keio University School Of Medicine , National Institutes Of Health , Princeton University , Soros Foundation , Technology Agency , Takeda Pharmaceuticals Science Frontier Fund , Ludwig Cancer Foundation , Scully Family Initiative , Jean Perkins Foundation , Stanford University , Keio University School , National Institutes , Bright Focus , Howard Hughes Medical Institute Hanna , Fellows Program , Japan Science , Jean Perkins , ஒன்றுபட்டது மாநிலங்களில் , காற்றின் அன்றேஅஸ்ஸோன் ,

Study reveals immune driver of brain aging

Study reveals immune driver of brain aging
Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.
Jan 20
2021
Katrin Andreasson is the senior author of a study that identifies a particular set of immune cells as a key driver of mental aging.
Steve Fisch
Suppose Smokey Bear were to lose it and start setting forest fires instead of putting them out. That roughly describes the behavior of certain cells of our immune system that become increasingly irascible as we grow older. Instead of stamping out embers, they stoke the flames of chronic inflammation. ....

United States , Steve Fisch , Amit Joshi , Qian Wang , Congcong Wang , Daria Mochly Rosen , Peter Moon , Ravi Majeti , Stanford Bio , Geraldj Lieberman , Frank Longo , Aarooran Durairaj , Bruce Goldman , Irving Weissman , Paras Minhas , Amanda Rubin , Esha Gauba , Amira Latif Hernandez , Katrin Andreasson , Stanford Innovation Fund , American Heart Association , Burroughs Wellcome Fund , Keio University School Of Medicine , Office Of Communication Public Affairs , Stanford University School Of Medicine , Technology Agency ,

Stanford study reveals immune driver of brain aging

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Suppose Smokey the Bear were to go on a tear and start setting forest fires instead of putting them out. That roughly describes the behavior of certain cells of our immune system that become increasingly irascible as we grow older. Instead of stamping out embers, they stoke the flames of chronic inflammation.
Biologists have long theorized that reducing this inflammation could slow the aging process and delay the onset of age-associated conditions, such as heart disease, Alzheimer s disease, cancer and frailty, and perhaps even forestall the gradual loss of mental acuity that happens to nearly everyone.
Yet the question of what, exactly, causes particular cells of the immune system to kick into inflammatory overdrive has lacked a definitive answer. ....

United States , Margarita Gallardo , Amit Joshi , Qian Wang , Congcong Wang , Daria Mochly Rosen , Peter Moon , Ravi Majeti , Stanford Bio , Geraldj Lieberman , Frank Longo , Aarooran Durairaj , Bruce Goldman , Irving Weissman , Paras Minhas , Amanda Rubin , Esha Gauba , Amira Latif Hernandez , Katrin Andreasson , Stanford Innovation Fund , American Heart Association , Burroughs Wellcome Fund , Keio University School Of Medicine , Stanford University School Of Medicine , Technology Agency , Ludwig Cancer Foundation ,