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Fierce Pharma Asia—Takeda's Maverick buyout; Brii COVID antibodies' trial halt; Dr. Reddy's generic Lipitor recall


Takeda, Brii Biosciences and Dr. Reddy s Laboratories made our news this week. (Google)
Takeda is buying its partner Maverick Therapeutics for its T-cell engager platform. The NIH has ended a clinical study testing Brii Biosciences anti-coronavirus antibody cocktail in hospitalized patients. Dr. Reddy s Laboratories is pulling a large volume of its generic Lipitor off U.S. pharmacy shelves due to impurities. And more.
Takeda exercised an option to buy out Maverick Therapeutics as part of a collaboration deal penned in early 2017. For up to $525 million upfront, Takeda’s getting full control of Maverick’s COBRA T-cell engager platform and the cancer pipeline built around it. These assets include lead candidate MVC-101, now known as TAK-186, which is in a phase 1/2 study in solid tumors that express EGFR. ....

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Takeda's Growth and Emerging Markets Business Unit Aims to Deliver Double-Digit Revenue Growth Over Next Decade1


Takeda Pharmaceutical Company Limited
Takeda’s Growth and Emerging Markets Business Unit Aims to Deliver Double-Digit Revenue Growth Over Next Decade1
Friday, March 12, 2021 11:40AM IST (6:10AM GMT)
 
Aiming for Revenues of JPY 1 Trillion (approximately US$9 Billion2) by FY2030
Double-Digit Revenue Growth Expected to be Driven by a Balanced and Focused Geographic Presence, Portfolio of 14 Global Brands and Wave 1 Pipeline Assets
Commitment to Patient Access to Medicines and Addressing Unmet Patient Needs in Emerging Markets Underpin Sustainable Growth
 
(TSE:4502/NYSE:TAK) (“Takeda”) today outlined its ambition for above-market, double-digit revenue growth of its Growth and Emerging Markets Business Unit (“GEM BU”). The revenue goal of JPY 1 trillion (approximately US$9 billion) by FY2030 represents more than doubling of current revenues in GEM BU. This potential growth will be primarily driven by a balanced geographical focus and targ ....

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Ultrarare disease specialists top 2021's pricey drugs list, but Takeda, Merck KGaA meds rank, too


Mar 9, 2021 12:12pm
Eiger BioPharmaceuticals Zokinvy, recently approved by the FDA for ultrarare rapid-aging diseases that affect an estimated 600 children worldwide, is the most expensive drug in U.S. pharmacies in 2021, according to GoodRx.(Jacoblund)
Eiger BioPharmaceuticals in November snagged FDA clearance for Zokinvy for ultra-rare rapid-aging diseases that affect an estimated 600 people worldwide. Orphan drugs that treat small patient populations typically come with high prices, but Zokinvy’s sticker price now beats them all in U.S. pharmacies.
At an estimated monthly price of $86,000, or more than $1 million a year, Zokinvy’s now the most expensive pharmacy drug in the U.S. as of February, according to a list compiled by GoodRx. The ranking focuses on monthly prices and doesn’t include drugs administered by doctors. ....

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Takeda keeps divestment spree rolling with $1.2B sale of diabetes meds to Japanese firm Teijin


Takeda s latest sale brings its total divestment value up to about $12.9 billion. (Takeda)
After inking a slate of geography-specific product selloffs last year, Takeda has turned back to Japan.
Takeda locked up a deal to sell four Type 2 diabetes meds in Japan to local drugmaker Teijin Pharma for 133 billion Japanese yen ($1.2 billion), freeing up the company to focus on its core businesses in gastroenterology, rare diseases, plasma-derived therapies, oncology and neuroscience.
The move is the latest in Takeda s selloff spree, linked to a divesture goal it set alongside its Shire merger. The company has already exceeded its $10 billion target, but has shown no sign of slowing down, as it continued to shave off noncore products late into 2020 and early 2021. ....

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