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New study uncovers potential therapeutic target for lupus

New study uncovers potential therapeutic target for lupus
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United States , Maryx Oriordan , Basel Abuaita , Jasons Knight , Emily Henderson , University Of Michigan , Michigan Medicine , Gautam Sule , ஒன்றுபட்டது மாநிலங்களில் , ஜேசன்கள் நைட் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் , மிச்சிகன் மருந்து , கௌதம் சூளே ,

Leading Lupus Researchers Recognized for Exceptional Work in the Field

Leading Lupus Researchers Recognized for Exceptional Work in the Field
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WASHINGTON, Feb. 3, 2021 /PRNewswire/ The Lupus Foundation of America (LFA) announced today the recipients of its most prestigious annual awards, recognizing three leading lupus scientists. This year, the LFA presented the Evelyn V. Hess Award to Joan T. Merrill, MD, Oklahoma Medical Research Foundation (OMRF) and the Mary Betty Stevens Young Investigator Prize to Andrea Knight, MD, MSCE, Hospital for Sick Children (SickKids) and Jason S. Knight, MD, PhD, University of Michigan. Both awards are selected through a peer-reviewed process, and this year s Mary Betty Stevens Young Investigator Prize resulted in a tie between two scientists. ....

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Circulating antiphospholipid antibodies drive endothelial cell activation in COVID-19

Circulating antiphospholipid antibodies drive endothelial cell activation in COVID-19
With the emergence of COVID-19 (coronavirus disease 2019), researchers have been closely investigating the complex interplay between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the human immune system, and COVID-19 disease severity.
Signaling proteins called cytokines cascade up to dangerous levels, leading to a cytokine storm that damages the body s cells (self). High levels of intravascular neutrophil extracellular traps (NETs) or inflammatory cell remnants amplify thrombosis. Synergistically, all of these results in macrovascular and microvascular thrombosis during a SARS-CoV-2 infection.
Although the endothelial cell activation is identified as part of the COVID-19 thrombo-inflammatory storm, this activation s upstream mediators are unknown. In a recent ....

Yogendra Kanthi , Jasons Knight , Ramya Dwivedi , Endothelial Cell , Corona Virus , Coronavirus Disease Covid 19 , C Reactive Protein , D Dimer , Immune System , Sars Cov 2 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , யோகேந்திரா காந்தி , ஜேசன்கள் நைட் , ரம்யா டுவிவேடி , கொரோனா வைரஸ் , நோய் எதிர்ப்பு சக்தி அமைப்பு , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,