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Tool helps predicts who will respond best to targeted prostate cancer therapy


New ‘nomogram’ opens the door to improved personalized treatments, UCLA-led study shows
UCLA
Based on the study, researchers also created an online risk calculator that forecasts the probability of overall and progression-free survival in response to LuPSMA.
Denise Heady |
July 8, 2021
A new prognostic tool developed by researchers from the UCLA Jonsson Comprehensive Cancer Center and five other institutions helps predict which men with advanced metastatic prostate cancer will respond favorably to a novel targeted therapy.
The tool, described in a study published today in Lancet Oncology, analyzes a wide spectrum of imaging and clinical data and is intended to assist physicians considering treating patients with Lutetium-177 prostate-specific membrane antigen, or LuPSMA. ....

United States , Baden Wüberg , Wolfgang Fendler , Wesley Armstrong , Michael Hofman , Rouzbeh Esfandiari , Uwe Haberkorn , Ebrahim Delpassand , Matthew Rettig , Clemens Kratochwil , Ken Herrmann , Johannes Czernin , David Elashoff , Tristan Grogan , Shahneen Sandhu , Boris Hadaschik , Matthias Eiber , Robert Tauber , Andrei Gafita , David Geffen School Of Medicine , Jonsson Cancer Center , Peter Maccallum Cancer Center , Drug Administration , Jonsson Comprehensive Cancer Center , Essen University Hospital , Heidelberg University Hospital ,