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Pioneering single-dose radiotherapy for breast cancer treatment


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A breast cancer therapy that requires just one shot of radiotherapy is as effective as traditional radiotherapy, and avoids potential damage to nearby organs, according to a paper by UCL experts.
The results, published in the
British Journal of Cancer, mean that eight out of ten patients who receive the treatment, TARGIT-IORT, will not need a long course of post-operative external beam radiotherapy (EBRT). These results strengthen and expand previously published outcomes.
Patients who received the treatment are less likely to go on to experience fatal cardiovascular disease such as heart attacks, lung problems or other cancers. As well as avoiding scattered radiation from EBRT that can damage nearby vital organs, delivering TARGIT-IORT during the lumpectomy procedure seems to lower the likelihood of death if patients do go on to develop cardiovascular disease, protecting in a drug-like manner. This was the case even when EBRT was also given post-operati ....

United States , United Kingdom , University College , New South Wales , Frederik Wenz , Michael Alvarado , David Mcready , Jeffreys Tobias , Richard Hoefer , Wolfgang Eiermann , David Joseph , Lorenzo Vinante , Christobel Saunders , Tammy Corica , Elena Sperk , Samuele Massarut , Mary Falzon , Gloria Petralia , Michael Baum , Wojciech Polkowski , Jane Bolger , Dennis Holmes , Max Bulsara , Fernando Bozza , Douglas Brown , Jens Blohmer ,