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The incredible, variable bacteria living in your mouth


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IMAGE: Micrograph showing Rothia cells (light blue) in their native habitat, a bacterial biofilm scraped from the human tongue.
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Credit: Photo credit: Jessica Mark Welch, Marine Biological Laboratory.
Bacteria often show very strong biogeography - some bacteria are abundant in specific locations while absent from others - leading to major questions when applying microbiology to therapeutics or probiotics: how did the bacteria get into the wrong place? How do we add the right bacteria into the right place when the biogeography has gotten out of whack ?
These questions, though, have one big obstacle, bacteria are so tiny and numerous with very diverse and complicated populations which creates major challenges to understanding which subgroups of bacteria live where and what genes or metabolic abilities allow them to thrive in these wrong places. ....

Jessica Mark Welch , Garyg Borisy , Colleen Cavanaugh , Mark Welch , Edwardc Jeffrey , Jessical Mark Welch , Colleenm Cavanaugh , Department Of Organismic , Harvard University , Forsyth Institute , Marine Biological Laboratory , University Of Chicago , Department Of Medicine , Genome Biology , Evolutionary Biology , Woods Hole , Human Microbiome Project , Marine Biological , ஜெசிகா குறி வெல்ச் , சக கவனக்குக்ஹ் , குறி வெல்ச் , ஹார்வர்ட் பல்கலைக்கழகம் , ஃபார்ஸித் நிறுவனம் , கடல் உயிரியல் ஆய்வகம் , பல்கலைக்கழகம் ஆஃப் சிகாகோ , துறை ஆஃப் மருந்து ,

Microbes in dental plaque look more like relatives in soil than those on the tongue


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From the perspective of A. Murat Eren, PhD, the mouth is the perfect place to study microbial communities. Not only is it the beginning of the GI tract, but it s also a very special and small environment that s microbially diverse enough that we can really start to answer interesting questions about microbiomes and their evolution, said Eren, an assistant professor in the Department of Medicine at the University of Chicago.
There s a surprising amount of site specificity, in that you find defined patterns of microbes in different areas of the mouth the microbes associated with the tongue are very different from those on the plaque on your teeth, he continued. Your tongue microbes are more similar to those living on someone else s tongue than they are to those living in your throat or on your gums! ....

Hyde Park , United States , Jessica Mark Welch , Abigailc Schmid , Mahmoud Yousef , Nora Downey , Floyde Dewhirst , Hillaryg Morrison , Lin Xing Chen , Institut Fran , Sonny Tm Lee , Amyd Willis , Karen Lolans , Mark Welch , Tomo Delmont , Simon Roux , Andrear Watson , University Of California , Craniofacial Research Grants , Frankr Lillie Research Innovation Award , Us Department Of Energy , University Of Washington , University Of Chicago Medicine Biological Sciences , Forsyth Institute , Duchossois Center , University Of Chicago ,