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UVA researchers make major strides in harnessing stem cells to battle disease Published Tuesday, Jun. 29, 2021, 12:00 am Join AFP s 100,000+ followers on Facebook Purchase a subscription to AFP Subscribe to AFP podcasts on iTunes and Spotify News, press releases, letters to the editor: augustafreepress2@gmail.com The tiny mouse embryo has a heart that beats. Its muscles, blood vessels, gut and nervous system are beginning to develop. But this embryo is unusual: it was made in a lab, out of mouse embryonic stem cells, and represents the most sophisticated in vitro (in a dish) model of a mammal ever so created. This new model, developed at the University of Virginia School of Medicine by Christine and Bernard Thisse, is a major step forward in scientists’ efforts to mimic the natural development of a mammal by using stem cells. Its existence is a wonder that will help scientists understand mammalian development, battle diseases, create new drugs and, eventually, grow tissues

Bernard thisseJonathan fillatrePeng fei xuRicardo moraes borgesChristine thisseNature communicationsDepartment of cell biologyUniversity of virginiaJefferson trustUniversity of virginia school medicineVirginia schoolCell biologyMaraysa de oliveira meloஇயற்கை தகவல்தொடர்புகள்துறை ஆஃப் செல் உயிரியல்பல்கலைக்கழகம் ஆஃப் வர்ஜீனியா