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VIDEO: This video shows a beating mouse heart crafted from stem cells at the University of Virginia School of Medicine. The work represents a major step forward in scientists efforts to. view more
Credit: Courtesy Thisse lab at UVA.
The tiny mouse embryo has a heart that beats. Its muscles, blood vessels, gut and nervous system are beginning to develop. But this embryo is unusual: It was made in a lab, out of mouse embryonic stem cells, and represents the most sophisticated in vitro (in a dish) model of a mammal ever so created.
This new model, developed at the University of Virginia School of Medicine by Christine and Bernard Thisse, is a major step forward in scientists efforts to mimic the natural development of a mammal by using stem cells. Its existence is a wonder that will help scientists understand mammalian development, battle diseases, create new drugs and, eventually, grow tissues and organs for people in need of transplants.
BrazilBernard-thisseJonathan-fillatrePeng-fei-xuRicardo-moraes-borgesTaochengChristine-thisseNature-communicationsDepartment-of-cell-biologyUniversity-of-virginiaJefferson-trustUniversity-of-virginia-school-medicineUVA researchers make major strides in harnessing stem cells to battle disease
Published Tuesday, Jun. 29, 2021, 12:00 am
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The tiny mouse embryo has a heart that beats. Its muscles, blood vessels, gut and nervous system are beginning to develop. But this embryo is unusual: it was made in a lab, out of mouse embryonic stem cells, and represents the most sophisticated in vitro (in a dish) model of a mammal ever so created.
This new model, developed at the University of Virginia School of Medicine by Christine and Bernard Thisse, is a major step forward in scientists’ efforts to mimic the natural development of a mammal by using stem cells. Its existence is a wonder that will help scientists understand mammalian development, battle diseases, create new drugs and, eventually, grow tissues
BrazilBernard-thisseJonathan-fillatrePeng-fei-xuRicardo-moraes-borgesTaochengChristine-thisseNature-communicationsDepartment-of-cell-biologyUniversity-of-virginiaJefferson-trustUniversity-of-virginia-school-medicine