How to Grow a Mouse Embryo in a Dish
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Boffins grow mouse embryo on petri dish in major step for human organ transplants
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Scientists create mouse embryo with a beating heart from stem cells
UVA
UVA
An extraordinary new study has detailed the development of a nearly complete mouse embryo – with muscles, blood vessels and a tiny beating heart – grown in a lab dish out of stem cells. The research presents the most sophisticated “embryo in a dish” created to date, offering essential new innovations on the road to growing replacement human organs in a lab.
The new research comes out of the Thisse Lab at the University of Virginia School of Medicine. Led by Christine and Bernard Thisse, the scientists have been working for years to find a way to build functional embryos out of stem cells.
Science fictionâs promise of creating organs for study or transplant is another step closer to reality, thanks to a tiny, manmade embryonic mouse in a University of Virginia School of Medicine laboratory.
Its little heart beating, its muscles, blood vessels, gut and nervous system beginning to take shape, the embryoid mouse is a major step in helping scientists understand how mammals develop.
B. Thisse
The technique to create the mouse, called an embryoid to distinguish it from a natural embryo, was developed by researchers Bernard and Christine Thisse, who discovered ways to stimulate stem cells from zebrafish to grow and develop into full fish back in 2014.