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New technique uses high-throughput sequencing to obtain ultra-high-resolution images of gene expression

The 30,000 or so genes making up the human genome contain the instructions vital to life. Yet each of our cells expresses only a subset of these genes in their daily functioning. The difference between a heart cell and a liver cell, for example, is determined by which genes are expressed and the correct expression of genes can mean the difference between health and disease. ....

United States , Jun Hee Lee , Emily Henderson , University Of Michigan Medical School , Department Of Molecular Integrative Physiology , Michigan Medical School , Michigan Medicine , Hee Lee , Associate Professor , Ene Expression , High Throughput Sequencing , Imaging Techniques , Medical School , ஒன்றுபட்டது மாநிலங்களில் , ஜூன் ஹீ லீ , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் மருத்துவ பள்ளி , துறை ஆஃப் மூலக்கூறு ஒருங்கிணைந்த உடலியல் , மிச்சிகன் மருத்துவ பள்ளி , மிச்சிகன் மருந்து , ஹீ லீ , இணை ப்ரொஃபெஸர் ,

Microscopic imaging without a microscope?

A new technique uses high-throughput sequencing, instead of a microscope, to obtain ultra-high-resolution images of gene expression from a tissue slide. ....

United States , Myungjin Kim , Jun Hee Lee , Chun Seok Cho , Yichen Si , Glenn Foundation , Michigan Economic Development Corporation , University Of Michigan Medical School , Chan Zuckerberg Initiative , Frankel Cardiovascular Center , Department Of Molecular Integrative Physiology , Michigan Medical School , Michigan Medicine , Sung Rye Park , Jer En Hsu , Goo Jun , Hyun Min , Frankel Cardiovascular Center Inaugural , American Association , Liver Diseases , Taiwan Government Scholarship , Michigan Economic Development , Spatial Transcriptome Using Seq Scope , Cell Biology , Medicine Health , ஒன்றுபட்டது மாநிலங்களில் ,