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New cellular atlas maps out healthy and cancerous breast tissue

Date Time
New cellular atlas maps out healthy and cancerous breast tissue
WEHI researchers have documented the diversity of cells in the human breast, explaining the relationship between healthy breast cells and breast cancer cells.
The diversity of cells in the human breast has been
documented in a new ‘RNA atlas’.
The research, which relied on expertise spanning from breast cancer biology through to bioinformatics, measured gene expression in single cells taken from healthy women and cancerous breast tissue, including tissue carrying a faulty BRCA1 gene. This enabled the researchers to create an ‘RNA atlas’ that details the different cells found in these tissues. ....

Tony Papenfuss , Jane Visvader , Geoff Lindeman , Gordon Smyth , Yunshun Chen , Rachel Joyce , Bhupinder Pal , Stephen Wilcox , Jocelyn Penington , Vanessa Bryant , Nina Tubau Ribera , Bianca Capaldo , National Health , Qualtrough Cancer Research Fund , Michael Heine Family Foundation , Ian Potter Foundation , Australian Cancer Research Foundation , National Breast Cancer Foundation , Research Council , Olivia Newton John Cancer Research Institute , Professor Jane Visvader , Professor Gordon Smyth , Professor Geoff , Professor Visvader , Professor Smyth , Victorian Cancer Biobank ,

Microscopic behaviour of developing breast cells uncovered

An improved high-tech fluorescence microscopy technique is allowing researchers to film cells inside the breast as never seen before. Dr Caleb Dawson. ....

Jane Visvader , Anne Rios , Geoffrey Lindeman , Geoff Lindeman , Caleb Dawson , Scott Mueller , National Health , Doherty Institute , Australian Cancer Research Foundation , National Breast Cancer Foundation , Research Council , Professor Jane Visvader , Nature Protocols , Dynamic Imaging , Professor Visvader , Professor Geoff Lindeman , Medical Research Council , Australian Government , Walter And Eliza Hall Institute , Medical Research , Cancer Research , Breast Cancer , Immune Cells , Stem Cells , அன்னே ரியோஸ் , ஜெஃப்ரி ழிந்தெமாங் ,

Microscopic behavior of developing breast cells uncovered

An improved high-tech fluorescence microscopy technique is allowing researchers to film cells inside the breast as never seen before.

This new protocol provides detailed instructions on how to capture hi-res movies of cell movement, division and cooperation, in hard-to-reach regions of breast tissue.

The technology - called multiphoton microscopy - uses infrared lasers to illuminate fluorescently labelled breast cells without harming them, so that elusive cell behaviours can be observed within living tissue. ....

Jane Visvader , Anne Rios , Geoff Lindeman , Caleb Dawson , Scott Mueller , National Health , Doherty Institute , Australian Cancer Research Foundation , National Breast Cancer Foundation , Research Council , Professor Jane Visvader , Nature Protocols , Dynamic Imaging , Professor Visvader , Professor Geoff Lindeman , Medical Research Council , Australian Government , Cell Biology , அன்னே ரியோஸ் , ஜியோஃப் ழிந்தெமாங் , காலேப் டாசன் , ஸ்காட் முல்லர் , தேசிய ஆரோக்கியம் , டோவர்டீ நிறுவனம் , ஆஸ்திரேலிய புற்றுநோய் ஆராய்ச்சி அடித்தளம் , தேசிய மார்பக புற்றுநோய் அடித்தளம் ,