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A team of researchers has developed a novel therapy that could be effective for different types of cancers. The study, published in the journal Cancer Discovery, indicates that the therapeutic agent shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive. Translating these findings into effective cancer therapies for patients is a high priority, said researcher Jian Jin from Mount Sinai in the US. According to the researchers, the therapy is an engineered molecule, MS21, that causes the degradation of AKT, an enzyme that is overly active in many cancers.
This study laid out evidence that pharmacological degradation of AKT is a viable treatment for cancers with mutations in certain genes, the researchers said.
Novel therapy might be effective in many cancers
By IANS |
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New York, July 25 : A team of researchers has developed a novel therapy that could be effective for different types of cancers.
The study, published in the journal Cancer Discovery, indicates that the therapeutic agent shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive. Translating these findings into effective cancer therapies for patients is a high priority., said researcher Jian Jin from Mount Sinai in the US.
According to the researchers, the therapy is an engineered molecule, MS21, that causes the degradation of AKT, an enzyme that is overly active in many cancers.
Novel therapeutic agent could be effective for treating cancers with certain gene mutations
Mount Sinai researchers have developed a therapeutic agent that shows high effectiveness in vitro at disrupting a biological pathway that helps cancer survive, according to a paper published in
Cancer Discovery, a journal of the American Association for Cancer Research, in July.
The therapy is an engineered molecule, named MS21, that causes the degradation of AKT, an enzyme that is overly active in many cancers. This study laid out evidence that pharmacological degradation of AKT is a viable treatment for cancers with mutations in certain genes.
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