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Research finds Cannabis terpenes as a promising new target for pain therapies


Research finds Cannabis terpenes as a promising new target for pain therapies
When it comes to the medicinal and therapeutic properties of
Cannabis sativa, an unsolved mystery is whether there exists an entourage effect, whereby the pain-relieving effects of the plant as a whole are greater than any of its individual parts. New research from the University of Arizona Health Sciences has found evidence that favors the entourage effect theory and positions
Cannabis terpenes, the part of the plant that provides flavor and aroma, as a promising new target for pain therapies that would require lower doses and produce fewer side effects. ....

Attila Kerestztes , John Streicher , Ryan Hecksel , Justin Lavigne , Emily Henderson , Uarizona Health Sciences Comprehensive Pain , Drug Administration , University Of Arizona Health Sciences , College Of Medicine , Addiction Center , Arizona Health Sciences , Health Sciences Comprehensive Pain , ஜான் ஸ்ட்ரீச்சர் , ஜஸ்டின் லவிக்னெ , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் அரிசோனா ஆரோக்கியம் அறிவியல் , கல்லூரி ஆஃப் மருந்து , அரிசோனா ஆரோக்கியம் அறிவியல் , ஆரோக்கியம் அறிவியல் விரிவான வலி ,

The entourage effect: Is cannabis more than just THC and CBD?


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Is there merit to the hypothesis that whole-plant extracts are more effective than isolating specific cannabinoids such as THC or CBD?
A recently published study in the journal
Scientific Reports is presenting evidence to suggest molecules called terpenes synergistically interact with cannabinoids to contribute to the therapeutic effects of cannabis. The research supports a controversial hypothesis dubbed the entourage effect, which claims the medical benefits of cannabis are not due to single cannabinoids such as THC or CBD but rather the broader interactions between various compounds in the plant.
The idea behind the entourage effect first arose in the late 1990s after a team of researchers discovered several fatty acids can enhance the activity of endogenous cannabinoids. On their own these compounds do not affect cannabinoid receptors, but when combined with naturally occurring cannabinoids they can amplify receptor activation. ....

John Streicher , University Of Arizona Health Sciences , Scientific Reports , Arizona Health Sciences , Arizona Health , ஜான் ஸ்ட்ரீச்சர் , பல்கலைக்கழகம் ஆஃப் அரிசோனா ஆரோக்கியம் அறிவியல் , அறிவியல் அறிக்கைகள் , அரிசோனா ஆரோக்கியம் அறிவியல் , அரிசோனா ஆரோக்கியம் ,