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Some coronavirus mutations may help it evade immune system's T-killer cells: study

Updated:
March 08, 2021 15:26 IST
The researchers sequenced 750 genomes of the novel coronavirus from infected individuals and analysed the mutations
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Artistic 3D-rendering of a T cell fighting with SARS-CoV-2 (not to scale). Credit: Benedikt Agerer / CeMM

The researchers sequenced 750 genomes of the novel coronavirus from infected individuals and analysed the mutations
Some mutations in the novel coronavirus may not only enable it to evade antibodies, but also make the virus unrecognisable to the immune system s T-killer cells, says a new study which could aid in the further development of vaccines.
While antibodies dock directly onto viruses to neutralise them, the scientists, including those from the Medical University of Vienna in Austria, said the T-killer cells recognise viral protein fragments on infected cells and subsequently kill them to stop virus production. ....

Johannes Huppa , Judith Aberle , Andreas Bergthaler , University Of Vienna , Medical University , Cell Immunology , Cell Biology , Molecular Biology , Corona Virus , Covid 19 , Cemm Research Center For Molecular Medicine Of The Austrian Academy Sciences , ஜூடித் அபேர்லே , பல்கலைக்கழகம் ஆஃப் வியன்னா , மருத்துவ பல்கலைக்கழகம் , செல் நோயெதிர்ப்பு , செல் உயிரியல் , மூலக்கூறு உயிரியல் , கொரோனா வைரஸ் , தடுப்பு மருந்துகள் ,

Scientists from the Medical University of Vienna in Austria said the T-killer cells identify viral fragments of protein on infected cells and eventually destroy them to prevent virus production.

A recent sudy suggests certain mutations in the novel coronavirus may not only allow it to escape neutralisation but also make the virus unidentifiable to the immune system's T-killer' cells, which could aid in the further development of vaccines. ....

Johannes Huppa , Judith Aberle , Andreas Bergthaler , University Of Vienna , Medical University , Cell Immunology , Novel Coronavirus , Immune System , ஜூடித் அபேர்லே , பல்கலைக்கழகம் ஆஃப் வியன்னா , மருத்துவ பல்கலைக்கழகம் , செல் நோயெதிர்ப்பு , நோய் எதிர்ப்பு சக்தி அமைப்பு ,

Some coronavirus mutations may help it evade immune system's T-killer cells, say scientists

Some coronavirus mutations may help it evade immune system s T-killer cells, say scientists
The researchers sequenced 750 genomes of the novel coronavirus from infected individuals and analysed mutations for their potential to alter T cell epitopes.
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By PTI
LONDON: Some mutations in the novel coronavirus may not only enable it to evade antibodies, but also make the virus unrecognisable to the immune system s T-killer cells, says a new study which could aid in the further development of vaccines.
While antibodies dock directly onto viruses to neutralise them, the scientists, including those from the Medical University of Vienna in Austria, said the T-killer cells recognise viral protein fragments on infected cells and subsequently kill them to stop virus production. ....

City Of , United Kingdom , Johannes Huppa , Judith Aberle , Andreas Bergthaler , University Of Vienna , Medical University , Cell Immunology , Covid 19 , Corona Virus , Tkiller Cells , Covid Vaccination Research , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , ஜூடித் அபேர்லே , பல்கலைக்கழகம் ஆஃப் வியன்னா , மருத்துவ பல்கலைக்கழகம் , செல் நோயெதிர்ப்பு , கொரோனா வைரஸ் ,