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New theranostic approach reduces tumor volume and increases survival in NET study


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IMAGE: Representative maximum intensity projection PET/CT images of AR42J tumor-bearing female Balb/c nude mice following injection of 64Cu-CuSarTATE (3 MBq, 0.24 nmol of peptide) at 1 and 4 hours post injection..
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Credit: Images created by associate professor Carleen Cullinane (Peter MaCallum Cancer Centre).
Reston, Virginia A pair of copper radionuclides that target the somatostatin receptor overexpressed in neuroendocrine tumors has proven successful in identifying tumors and improving survival. According to new research published in the December issue of
The Journal of Nuclear Medicine, the imaging agent 64Cu-CuSarTate produced high-quality positron emission tomography (PET) images in a mouse model of neuroendocrine tumors, while its therapeutic counterpart, 67Cu-CuSarTate, was highly effective in reducing tumor volume and extending lifespan. The research also demonstrated the advantages of delivering the radionuclide therapy as ....

United States , South Wales , South Australia , Pauls Donnelly , Matthewj Harris , Kevin Kuan , Rebecca Maxey , Susan Jackson , Peterd Roselt , David Binns , Rodneyj Hicks , Charmainem Jeffrey , Carleen Cullinane , Journal Of Nuclear Medicine , Sir Peter Maccallum Department Of Oncology , Clarity Pharmaceuticals Ltd , Media Center , Peter Maccallum Cancer Centre , School Of Chemistry , Centre For Cancer Imaging , Biotechnology Institute , University Of Melbourne , Sir Peter Maccallum Department , Research Division , Therapy Research Unit , Nuclear Medicine ,

New Theranostic Approach Reduces Tumor Volume and Increases Survival in Neuroendocrine Tumor Study


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New Theranostic Approach Reduces Tumor Volume and Increases Survival in Neuroendocrine Tumor Study
Reston, Virginia-A pair of copper radionuclides that target the somatostatin receptor overexpressed in neuroendocrine tumors has proven successful in identifying tumors and improving survival. According to new research published in the December issue of The Journal of Nuclear Medicine, the imaging agent
64Cu-CuSarTate produced high-quality positron emission tomography (PET) images in a mouse model of neuroendocrine tumors, while its therapeutic counterpart,
67Cu-CuSarTate, was highly effective in reducing tumor volume and extending lifespan. The research also demonstrated the advantages of delivering the radionuclide therapy as two fractionated doses, as opposed to one. ....

South Australia , Pauls Donnelly , Matthewj Harris , Kevin Kuan , Susan Jackson , Peterd Roselt , David Binns , Rodneyj Hicks , Charmainem Jeffrey , Carleen Cullinane , Journal Of Nuclear Medicine , Sir Peter Maccallum Department Of Oncology , Clarity Pharmaceuticals Ltd , Peter Maccallum Cancer Centre , School Of Chemistry , Centre For Cancer Imaging , Biotechnology Institute , University Of Melbourne , Sir Peter Maccallum Department , Research Division , Therapy Research Unit , Nuclear Medicine , Sir Peter Maccallum , Receptor Radionuclide Therapy , Highly Efficacious Against , Somatostatin Positive Neuroendocrine Tumor Model ,

Holidaymaker wins court battle against travel giant Lufthansa


Holidaymaker wins court battle against travel giant Lufthansa
William Cole For Mailonline
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A furious holidaymaker who had to pay almost £1,000 extra because an airline spelled his wife s name wrong on her Christmas holiday plane ticket has won his money back after taking them on in court.
Maxime Audet had to stump up for a new ticket after realising at the last minute that his wife Veronique s name had been spelled with two letters the wrong way round on the booking for their £2,000 festive trip to Canada last year.
German travel giants Lufthansa claimed the error was Mr Audet s and said they could not correct it administratively, demanding he pay for a whole new ticket or his wife not to travel at all. ....

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