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Q&A: How DNA detective work is helping crack complex diseases


Q&A: How DNA detective work is helping crack complex diseases
6 May, 2021 01:30 AM
6 minutes to read
Recent breakthroughs in genetics have transformed our understanding of many complex diseases. Image / 123RF
The human genetic code is mind-bogglingly complex - but it s a field of science
Professor Justin O Sullivan feels at home in. The deputy director of the University of Auckland s Liggins Institute, and a fellow of
the Office of the Prime Minister s Chief Science Advisor, will be giving his inaugural professorial lecture tomorrow afternoon about genetics, complex diseases and the microbiome. Science reporter
Jamie Morton chatted with him ahead of his talk. ....

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Bethesda's Gain Therapeutics Presents New GBA1 Parkinson's Disease Program Pre-clinical Data · BioBuzz


Compounds reverse the neurodegenerative process observed in a Parkinson’s disease in vivo model
Compounds are novel allosteric regulators that bind, stabilize and restore activity of mutated GCase
Compounds decrease both phosphorylated and aggregated α
-synuclein levels in vitro and in vivo
BETHESDA, Md., May 03, 2021 (GLOBE NEWSWIRE) Gain Therapeutics, Inc. (NASDAQ: GANX) (“Gain”), a biotechnology company focused on redefining drug discovery by using super-computational methods to target allosteric binding sites and guide enzymes back to their proper shape, today announced new pre-clinical data from its GBA1 Parkinson’s disease program. The findings were highlighted in a presentation at the XXVI International Association of Parkinsonism and Related Disorders (IAPRD) World Congress, a research conference dedicated to Parkinson’s disease and other disorders affecting muscle tone and motor control, being held virtually May 1-4, 2021. ....

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Investegate |Gain Therapeutics Announcements | Gain Therapeutics: Gain Therapeutics Strengthens Leadership Team with the Appointment of Four Industry Leaders to Its Board of Directors


Gain Therapeutics
Gain Therapeutics Strengthens Leadership Team with the Appointment of Four Industry Leaders to Its Board of Directors
Gain Therapeutics Strengthens Leadership Team with the Appointment of Four Industry Leaders to Its Board of Directors
BETHESDA, Md., Feb. 02, 2021 (GLOBE NEWSWIRE) Gain Therapeutics, Inc. (“Gain”) today announced the addition of Dov Goldstein, M.D., Gwen Melincoff, Claude Nicaise, M.D. and Hans Peter Hasler as independent members to its Board of Directors. The new board additions will provide strategic guidance as the company focuses on identifying and optimizing allosteric binding sites that have never before been targeted to unlock new treatment options for difficult-to-treat disorders characterized by protein misfolding. In conjunction with the new additions, Dr. Lorenzo Leoni and Dr. Marianne Bjordal will be stepping down from Board. ....

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