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We know a lot about Covid-19. Experts have many more questions


We know a lot about Covid-19. Experts have many more questions
A transmission electron micrograph of a SARS-CoV-2 virus particle.
NIAID
Less than a year and a half ago, the world was blissfully, dangerously ignorant of the existence of a coronavirus that would soon turn life on earth on its head.
In the 16 months since the SARS-CoV-2 virus burst into the global consciousness, we’ve learned much about this new health threat. People who contract the virus are infectious before they develop symptoms and are most infectious early in their illness. Getting the public to wear masks, even homemade ones, can reduce transmission. Vaccines can be developed, tested, and put into use within months. As they say, where there’s a will, there’s a way. ....

New York , United States , New Zealand , Rockefeller University , United Kingdom , South Korea , Andrews School , Ben Cowling , Emma Hodcroft , Soumya Swaminathan , Susan Weiss , Sarah Cobey , Ali Ellebedy , Krutika Kuppalli , John Moore , Adam Kucharski , Michael Osterholm , Stanley Perlman , Paul Bieniasz , Nahid Bhadelia , Maria Van Kerkhove , Akiko Iwasaki , Marion Koopmans , Vineet Menachery , Kristian Andersen , Saskia Popescu ,

Some experts fear next-generation Covid vaccines may be worse


Hyacinth Empinado/STAT
With Covid-19 vaccines, the world hopes to beat back the virus that causes the disease. But some scientists are increasingly concerned that, because of a quirk of our own biology, future iterations of the vaccines might not always be quite as effective as they are today.
The concerns stem from a phenomenon that is known as imprinting, sometimes called original antigenic sin, which is believed to affect how we respond to some pathogens.
In short, when your body is introduced to a particular threat for the first time either through infection or a vaccine that encounter sets your immune system’s definition of that virus and what immune weapons it needs to detect and protect against it in the future. ....

New York , United States , South Africa , University Of Rochester Medical Center , Scott Hensley , Vineet Menachery , John Mascola , Michael Worobey , Sarah Cobey , David Topham , Florian Krammer , Vaccine Research Center , National Institute Of Allergy , Finnish Institute For Health , University Of Turku , University Of Pennsylvania , University Of Chicago , York Influenza Center , University Of Texas Medical Branch In Galveston , University Of Arizona , Texas Medical Branch , Rochester Medical Center , New York Influenza Center , Icahn School , Mount Sinai Hospital , Finnish Institute ,