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July 6, 2021 By Deborah Borfitz July 6, 2021 | A trio of universities are putting their heads together to engineer a wirelessly controlled bioelectronic implant intended to help soldiers adapt to new time zones or drastic changes in their work schedules by releasing peptide-based therapies to harmonize their central and peripheral circadian clocks. The solicitation came from the Defense Advanced Research Projects Agency (DARPA) and the timeline is ambitious, with a first-in-human safety study expected to begin by 2025, according to Jonathan Rivnay, principal investigator of the project and assistant professor of biomedical engineering at Northwestern University. The project aims to create a Normalizing Timing of Rhythms Across Internal Networks of Circadian Clocks (aka NTRAIN) device, otherwise known as a “living pharmacy” that involves the engineering of cells that will secrete biologics based on an optoelectronic trigger and a communication signal from an exter

Isaac hiltonBlackrock neurotechOmid veisehJonathan rivnayDeborah borfitzFredw turekCarnegie mellonCarnegie mellon universityNorthwestern centerDefense advanced research projects agencyMassachusetts institute of technologyRice universityBroad agency announcementNorthwestern universityNormalizing timingRhythms across internal networks