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Research shows for the first time that protein complexes 'inflammasomes' are linked to obesity-related colon cancer


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New research presented at this year s European Congress on Obesity (held online, 10-13 May) finds evidence that structures called inflammasomes (a part of the innate immune system that helps to regulate inflammation) could play an important role in the development of obesity-associated colon cancer. The study is by Dr Victoria Catalán and Professor Gema Frühbeck, University Hospital Navarra and CIBEROBN, Instituto de Salud Carlos III, Pamplona, Spain, and colleagues.
Inflammasomes form part of the innate immune system which provides the first line of defence against pathogens using a wide range of physical, chemical, and biological responses.
Dysregulation of inflammasomes within visceral adipose tissue (VAT - fat that surrounds the organs) and in the colon can trigger prolonged episodes of inflammation, favouring the development of colon cancer (CC). The aim of this study was to explore whether obesity and CC influence the expression of different inflamma ....

Castillay Leóp , Salud Carlos , University Hospital Navarra , European Congress On Obesity , European Congress , Instituto De Salud Carlos , சலுத் கார்லோஸ் , ஐரோப்பிய காங்கிரஸ் ஆன் உடல் பருமன் , ஐரோப்பிய காங்கிரஸ் , இந்‌ஸ்டிடூடோ டி சலுத் கார்லோஸ் ,

Shadow and Bone is a cauldron of talent


Shadow and Bone is a cauldron of talent
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Many fantasy novels begin the same way: A person living in humble obscurity somehow becomes the Chosen One. Maybe they discover a hidden magical power they didn t realize they had, or find a petrified dragon s egg, or inherent an uncle s ring. One way or another, though, fate thrusts the hero on an epic adventure — and we, the readers, get to join her for the journey.
Real life doesn t usually work like that. Though there are exceptions; say, like when a very good casting director happens to take notice of an actor s work and then sweeps them up into what might very well be the best high fantasy adaptation since Peter Jackson s ....

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Mass vaccination site now open in Chatham County


Mass vaccination site in Chatham Co. to close early Thursday due to severe weather threat
By Blair Caldwell | March 17, 2021 at 4:15 PM EDT - Updated March 17 at 6:53 PM
CHATHAM COUNTY, Ga. (WTOC) - Chatham County’s mass vaccination site opened on Wednesday at the Gulfstream facility. Georgia Emergency Management Agency leaders say they can do about 2,000 vaccinations in one day. On their first day, the site just had a few hundred scheduled.
“I just have been waiting and waiting and waiting to get this vaccination so I am thrilled to be here,” said Stacey Valant of Savannah, who received a COVID-19 vaccine on Wednesday, ....

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GEMA reaching out to the Hispanic community and prepping for new phase


GEMA reaching out to the Hispanic community and prepping for new phase
GEMA reaching out to the Hispanic community and prepping for new phase
By Molly Godley | March 4, 2021 at 7:17 PM EST - Updated March 4 at 8:06 PM
ALBANY, Ga. (WALB) - Georgia Emergency Management Agency and Homeland Security (GEMA) said the Latino turnout for the COVID-19 vaccine has been low in Albany.
The state site has been open for nearly two weeks.
External Affairs Supervisor Lisa Rodriguez-Presley said they’ve heard the Latin community has concerns the site will check immigration documents or status.
GEMA External Affairs Supervisor, Lisa Rodriguez-Presley (Source: WALB) ....

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