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DIA 2021 to explore the potential of mRNA technology

DIA 2021 to explore the potential of mRNA technology
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United Kingdom , United States , Christopher Saeui , Albert Bourla , Girish Chopda , Philip Santangelo , National Center , Emory University School Of Medicine , Georgia Institute Of Technology , Translational Sciences , Office Of Rare Diseases Research , Dicerna Pharmaceuticals , Coulter Department Of Biomedical Engineering , Monday June , Rare Diseases Research , Advancing Translational Sciences , Coulter Department , Biomedical Engineering , Georgia Institute , Emory University School , Epstein Barr Virus , Bio Digital , Tidal Therapeutics , ஒன்றுபட்டது கிஂக்டம் , ஒன்றுபட்டது மாநிலங்களில் , பிலிப் சந்தங்கேளோ ,

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors
RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways.
Mostly.
So far, these promising drugs haven t been very useful in getting through to the well-protected brain to treat tumors or other maladies.
Now a multi-institutional team of researchers, led by Costas Arvanitis at the Georgia Institute of Technology and Emory University, has figured out a way: using ultrasound and RNA-loaded nanoparticles to get through the protective blood-brain barrier and deliver potent medicine to brain tumors. ....

Tobey Macdonald , Costas Arvanitis , Yutong Guo , Emily Henderson , Emory School Of Medicine , Oncology Program , Blood Disorders Center , Emory University , Georgia Institute Of Technology , Coulter Department Of Biomedical Engineering , University Of Cincinnati College Medicine , Georgia Institute , Assistant Professor , Coulter Department , Biomedical Engineering , Georgia Tech , Mechanical Engineering , Cincinnati College , Science Advances , Pediatric Neuro Oncology Program , Aflac Cancer , Blood Vessels , Brain Disease , Brain Tumor , Ell Death , Personalized Medicine ,

Breaching blood-brain barrier to deliver precious payloads

Georgia Institute of Technology
RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways.
Mostly.
So far, these promising drugs haven’t been very useful in getting through to the well-protected brain to treat tumors or other maladies.
Now a multi-institutional team of researchers, led by Costas Arvanitis at the Georgia Institute of Technology and Emory University, has figured out a way: using ultrasound and RNA-loaded nanoparticles to get through the protective blood-brain barrier and deliver potent medicine to brain tumors. ....

Tobey Macdonald , Costas Arvanitis , Yutong Guo , Emory School Of Medicine , Oncology Program , Blood Disorders Center , Emory University , Georgia Institute Of Technology , Coulter Department Of Biomedical Engineering , University Of Cincinnati College Medicine , Georgia Institute , Coulter Department , Biomedical Engineering , Georgia Tech , Mechanical Engineering , Cincinnati College , Science Advances , Pediatric Neuro Oncology Program , Aflac Cancer , டோபெய் மெக்டொனால்ட் , உணர்ச்சி பள்ளி ஆஃப் மருந்து , புற்றுநோயியல் ப்ரோக்ர்யாம் , இரத்தம் கோளாறுகள் மையம் , உணர்ச்சி பல்கலைக்கழகம் , ஜார்ஜியா நிறுவனம் ஆஃப் தொழில்நுட்பம் , கூல்டர் துறை ஆஃப் உயிர் மருத்துவ பொறியியல் ,

Breaching the blood-brain barrier to deliver precious payloads

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IMAGE: Georgia Tech Mechanical Engineering Ph.D. student Yutong Guo (left) and her mentor, assistant professor Costas Arvanitis, have developed a way to use ultrasonics to treat brain disease.
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Credit: Ashley Ritchey, Georgia Tech
RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways.
Mostly.
So far, these promising drugs haven t been very useful in getting through to the well-protected brain to treat tumors or other maladies. ....

United States , Emory University , Georgia Institute Of Technology , Tobey Macdonald , Costas Arvanitis , Yutong Guo , Blood Disorders Center , National Institutes Of Health , University Of Cincinnati College Medicine , Emory School Of Medicine , Oncology Program , Coulter Department Of Biomedical Engineering , Georgia Institute , Coulter Department , Biomedical Engineering , Georgia Tech , Mechanical Engineering , Cincinnati College , Science Advances , Pediatric Neuro Oncology Program , Aflac Cancer , National Institutes , ஒன்றுபட்டது மாநிலங்களில் , உணர்ச்சி பல்கலைக்கழகம் , ஜார்ஜியா நிறுவனம் ஆஃப் தொழில்நுட்பம் , டோபெய் மெக்டொனால்ட் ,