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Cambridge University scientists identify 200 approved drugs that could fight Covid

Cambridge University scientists identify 200 approved drugs that could fight Covid
cambridge-news.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from cambridge-news.co.uk Daily Mail and Mail on Sunday newspapers.

United Kingdom , Tony Kazourides , Namshik Han , Cambridge University , University Of Cambridge , Milner Therapeutics Institute , Gurdon Institute , Head Of Computational Research , Science Advances , Computational Research , Milner Therapeutics , ஒன்றுபட்டது கிஂக்டம் , கேம்பிரிட்ஜ் பல்கலைக்கழகம் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , மில்னர் சிகிச்சை நிறுவனம் , குர்டன் நிறுவனம் , கணக்கீட்டு ஆராய்ச்சி ,

Scientists identify 160 new drugs that could be repurposed against COVID-19

Scientists identify 160 new drugs that could be repurposed against COVID-19
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United Kingdom , Namshik Han , Tony Kouzarides , European Union Horizon , Cancer Research United Kingdom , Milner Therapeutics Institute , Gurdon Institute , University Of Cambridge Milner Therapeutics Institute , Head Of Computational Research , Science Advances , Computational Research , European Union , Cancer Research United , ஒன்றுபட்டது கிஂக்டம் , ஐரோப்பிய தொழிற்சங்கம் அடிவானம் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது கிஂக்டம் , மில்னர் சிகிச்சை நிறுவனம் , குர்டன் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் மில்னர் சிகிச்சை நிறுவனம் , கணக்கீட்டு ஆராய்ச்சி , ஐரோப்பிய தொழிற்சங்கம் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது ,

New class of compounds found to block coronavirus reproduction

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A human genetic mechanism hijacked by SARS-CoV-2, the coronavirus behind the COVID-19 pandemic, to help it spread also makes it vulnerable to a new class of drug candidates, a new study finds.
Led by researchers at NYU Grossman School of Medicine, a research team showed that coronavirus reproduction in infected human cells requires chemical changes made by the human protein METTL3 to RNA, a key form of genetic material. Additional human proteins involved in the recognition of modified RNA, YTHDF1 and YTHDF3, were also found to be important to the process.
Published online in
Genes and Development on June 24, the study showed for the first time that a molecular inhibitor of METTL3, designed by Storm Therapeutics Ltd and called STM2457, dramatically reduced in cell cultures the replication of both pandemic SARS-CoV-2 and, a less severe, seasonal coronavirus, HCoV-OC43, one cause of the common cold. ....

United Kingdom , Hannah Burgess , Tony Kouzarides , Kenneth Stapleford , Rebecca Grande , Angus Wilson , Wesley Blackaby , Daniel Depledge , Alan Hendrick , Elizabeth Vink , Puthankalam Srinivas Kalanghad , Jonathan Abebe , Ian Mohr , Letitia Thompson , Langone Health , National Institute Of Allergy , National Institutes Of Health , Perlmutter Cancer Center Support Grant , Gurdon Institute , University Of Cambridge , Department Of Microbiology , Grossman School Of Medicine , Storm Therapeutics Ltd , Department Of Pathology , Department Of Medicine , Mark Albertella At Storm Therapeutics Ltd ,

Coloring tumors reveals their bad influence

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IMAGE: Confocal micrographs of mouse small intestine with the Red2Onco technology. With Red2Onco, the oncogenic mutant clones (Red clones), and normal or wild-type clones (Yellow or Cyan clones) can be labeled.
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Credit: ©Yum/IMBA
Studies on cancer are limited by the threshold at which cellular transformations become clinically detectable. However, the very initial phase on the way to malignancy is histologically invisible, as the process originates from one single cell. In this early phase, a so-called seeding cell acquires an initial pro-cancerous mutation, also known as the first oncogenic hit , while being completely surrounded by normal tissue. To overcome the detection barrier, a team of researchers around IMBA group leader Bon-Kyoung Koo and University of Cambridge group leader Professor Benjamin D. Simons developed a laboratory system to dissect the pre-cancerous steps that remained under the radar up until present. ....

United Kingdom , Benjamin Simons , Bon Kyoung Koo , Benjamind Simons , Seungmin Han , University Of Cambridge , Austrian Federal Ministry Of Science , Gurdon Institute , Institute Of Molecular Biotechnology , Austrian Academy Of Sciences , Professor Benjamin , Min Kyu Yum , Bone Morphogenic Protein , Min Kyu , Molecular Biotechnology , Vienna Biocenter , Austrian Academy , Austrian Federal Ministry , Biomedical Environmental Chemical Engineering , Cell Biology , Developmental Reproductive Biology , Molecular Biology , ஒன்றுபட்டது கிஂக்டம் , பெஞ்சமின் சிமன்கள் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , ஆஸ்திரேலிய கூட்டாட்சியின் அமைச்சகம் ஆஃப் அறிவியல் ,

Academy of Medical Sciences announces election of new Fellows 2021

Cambridge scientists are among the new Fellows announced today by the Academy of Medical Sciences.
The greatest health advances rely on the findings of many types of research, and on multidisciplinary teams and cross-sector and global collaboration.
Professor Dame Anne Johnson, President of the Academy of Medical Sciences
The Academy of Medical Sciences has elected 50 prominent biomedical and health scientists to its respected and influential Fellowship. The new Fellows have been selected for their exceptional contributions to the advancement of medical science through innovative research discoveries and translating scientific developments into benefits for patients and the wider society.
Professor Dame Anne Johnson, President of the Academy of Medical Sciences, said: “I am truly delighted to welcome these 50 new Fellows to the Academy’s Fellowship, and I offer my congratulations to each of them on their exceptional contribution to bio ....

United Kingdom , City Of , Dame Anne Johnson , Franklin Aigbirhio , Brian Huntly , Ravindra Gupta , Adrian Liston , Babraham Institute , Homerton College , Academy Of Medical Sciences , Magdalene College , Churchill College , Department Of Clinical Neurosciences , Senior Group Leader , Academy Fellowship , Senior Group Leader Of The Gurdon Institute , Cambridge Stem Cell Institute , Group Leader , Royal Society Ep Abraham Professor , Head Of The Department Haematology , St John College , Department Of Applied Mathematics , University Of Cambridge Department Haematology , Department Of Chemistry , Senior Research , Cambridge Institute Of Therapeutic Immunology ,