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Study of mosquito protein could lead to treatments against life-threatening viruses


HIN
The mosquito protein AEG12 strongly inhibits the family of viruses that cause yellow fever, dengue, West Nile, and Zika and weakly inhibits coronaviruses, according to scientists at the National Institutes of Health (NIH) and their collaborators. The researchers found that AEG12 works by destabilizing the viral envelope, breaking its protective covering. Although the protein does not affect viruses that do not have an envelope, such as those that cause pink eye and bladder infections, the findings could lead to therapeutics against viruses that affect millions of people around the world. The research was published online in PNAS.
Scientists at the National Institute of Environmental Health Sciences (NIEHS), part of NIH, used X-ray crystallography to solve the structure of AEG12. Senior author Geoffrey Mueller, Ph.D., head of the NIEHS Nuclear Magnetic Resonance Group, said at the molecular level, AEG12 rips out the lipids, or the fat-like portions of the membrane that ....

Geoffrey Mueller , Lars Pedersen , Alexander Foo , Structure Function Group , National Institute Of Environmental Health Sciences , National Institutes Of Health , Nuclear Magnetic Resonance Group , West Nile , National Institutes , National Institute , Environmental Health Sciences , Magnetic Resonance Group , Environmental Health , Immune Response , Corona Virus , Covid 19 , ஜெஃப்ரி முல்லர் , லார்ஸ் பெடர்‌ஸெந் , அலெக்சாண்டர் ஃபூ , அமைப்பு செயல்பாடு குழு , தேசிய நிறுவனம் ஆஃப் சுற்றுச்சூழல் ஆரோக்கியம் அறிவியல் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , அணு காந்த அதிர்வு குழு , மேற்கு நைல் , தேசிய நிறுவனங்கள் , தேசிய நிறுவனம் ,

Commencement of Airborne Geophysical Survey at Donnelly River


BlackEarth Minerals
Highlights:
The survey will be undertaken by UTS Geophysics using a VTEM Max Time Domain EM system (Figure 1)
The survey will cover the entirety of E70/4825 (~80km2 ) and will be flown on 200m line spacing for a total of 390-line kilometres.
The survey will provide key information across the entire project with particular interest focused on the 3 anomalous magnetic and geochemical trends previously reported (see ASX announcement dated 27 January 2021).
The results of the survey will then be assessed and interpreted by the company’s Geophysical Consultants followed by further tailored programs of ground-based exploration activities.
The VTEM plan is a first time systematic program of exploration for Nickel-Copper- Platinum in this region ....

Western Australia , Donnelly River , Venture Minerals , Platinum Group Metals Ni , Blackearth Minerals , Time Domain , Geophysical Consultants , Donnelly River Project , Chalice Gold Mines , South West , மேற்கு ஆஸ்திரேலியா , டோநிலீ நதி , துணிகர தாதுக்கள் , வன்பொன் குழு உலோகங்கள் நி , நேரம் களம் , புவி இயற்பியல் ஆலோசகர்கள் , டோநிலீ நதி ப்ராஜெக்ட் , சாலிஸ் தங்கம் சுரங்கங்கள் , தெற்கு மேற்கு ,