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Making Sense Of Antibody Epitope Claims By Benjamin Pelletier, Haynes and Boone The antibody therapeutics industry has mushroomed into a sector whose value is estimated to reach $138.6 billion by 2024. 1 And this astounding economic growth has been accompanied by equally astonishing technological advancement. Obtaining certain types of patent rights to antibodies has become increasingly challenging in the United States. 2 To comprehend this evolution, we must first take a careful look at what antibodies are, and then understand how they are claimed in a patent. Antibodies And Patent Claims An antibody is, at its core, a professional binding molecule, whose sole purpose is to bind to its epitope – the three-dimensional arrangement of molecules to which it is attracted under the laws of physics. Each peptide subunit of an antibody contains a stretch of amino acid residues that are highly variable from one antibody to the next (aptly named the “variable re ....
E-Mail DNA sequencing of bacteria found in pigs and humans in rural eastern North Carolina, an area with concentrated industrial-scale pig-farming, suggests that multidrug-resistant Staphylococcus aureus strains are spreading between pigs, farmworkers, their families and community residents, and represents an emerging public health threat, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health. S. aureus is commonly found in soil and water, as well as on the skin and in the upper respiratory tract in pigs, other animals, and people. It can cause medical problems from minor skin infections to serious surgical wound infections, pneumonia, and the often-lethal blood-infection condition known as sepsis. The findings provide evidence that multidrug-resistant S. aureus strains are capable of spreading and possibly causing illness in and around factory farm communities in the U.S. a scenario the authors say researchers should continue to ....
Freehold Raceway concluded the Vinny Fusco Jr. Memorial Pacing Series this Friday (January 22), with a pair of finals. One saw a logical result, the other an upset. Tall Poppy N completed a sweep of the second division, for fillies and mares with a TrackMaster Horse Rating between 71.50 and 75.00 at the start of the series. Just like in the first two legs, George Brennan put her on the lead just after the quarter, and set comfortable fractions. In the stretch, she received a stiff challenge from Thaneeya, but Tall Poppy N held her at bay for a half-length win, in 1:56.3. The winner is owned by Curtin Anz Stable and trained by Kelvin Harrison, and paid $4.20 to win. ....