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Harnessing 19F as an agent in bio-NMR of large systems


Editorial Article: Harnessing 19F as an agent in bio-NMR of large systems
Watch this on-demand webinar to learn more about emerging and cutting-edge techniques in NMR
14 Jan 2021
The
19F-
13C TROSY principle opens exciting opportunities to probe structure, dynamics and interactions in large biomolecular systems, in which
19F-labels can be incorporated into either a protein or a nucleic acid residue. 
The fluorine atom is an extremely sensitive probe towards its chemical environment thanks to high CSA (chemical shift anisotropy); at the same time CSA also badly broadens the NMR-signals of
19F-labels in biomacromolecules. The TROSY effect can be used to combat CSA and narrow the linewidth of the ....

Gareth Morris , Haribabu Arthanari , Professor At Dana Farber Cancer Institute , Dana Farber Cancer Institute , Editorial Article , Assistant Professor , Dana Farber Cancer , Burkhard Luy , Harnessing 19f As An Agent In Bio Nmr Of Large Systems Selectscience , கரேத் மோரிஸ் , ப்ரொஃபெஸர் இல் டானா ஃபார்‌பர் புற்றுநோய் நிறுவனம் , டானா ஃபார்‌பர் புற்றுநோய் நிறுவனம் , தலையங்கம் கட்டுரை , உதவியாளர் ப்ரொஃபெஸர் , டானா ஃபார்‌பர் புற்றுநோய் ,