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Two monoclonal antibodies broadly neutralize SARS-CoV-2 variants of concern

Researchers in the United States and Canada have described the structural basis and mode of action for two monoclonal antibodies that potently neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19). ....

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Lameness prevention: Is a whole-body approach to navicular disease on the horizon?

The equine navicular enthesis organ, showing structures of the navicular apparatus. Image: Osborne, Blas-Machado, Cornille, Uhl
“Navicular” is a diagnosis that nobody wants to hear. The prognosis is often poor, resulting in full or partial retirement of the horse. Equine Science Foundation co-founder Paige LaBella looks at a review of the latest research, which suggests navicular syndrome might be preventable.
Navicular is usually associated with front foot pain and damage to the navicular bone, deep inside the hoof structure, and any of a number of structures around it.
But what if there was a way to prevent it through training? A promising review paper on navicular syndrome suggests this may be the case. ....

Elizabethw Uhl , Jean Luc Cornille , Uriel Blas , Michellel Osborn , Paige Labella , Graham Scarr , Equine Science Foundation , Science Foundation , Navicular Syndrome , Grand Prix , Structural Basis , Equine Navicular Apparatus , Premier Enthesis Organ , Veterinary Surgery , கிரஹாம் வடு , அறிவியல் அடித்தளம் , மாபெரும் ப்ரீ , கட்டமைப்பு அடிப்படையில் , கால்நடை அறுவை சிகிச்சை ,

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

Liji Thomas , Alpha Tauri , Stony Brook University , Brookhaven National Laboratory , Structural Basis , Human Cell Junction Protein , Fourier Shell Correlation , ஆல்பா ட Au ரி , ஸ்டோனி சிற்றாறு பல்கலைக்கழகம் , ப்ரூக்ஹவன் தேசிய ஆய்வகம் , கட்டமைப்பு அடிப்படையில் ,

What Happens at the End? | ScienceBlogs

Organisms with linear chromosomes have to solve the problem that DNA replication makes them shorter. This is due to the fact that DNA polymerase can only add bases to the terminal 3 -OH of a DNA chain. The DNA replication initiation complex uses RNA primers to provide the initial 3 -OH and to initiate lagging strand synthesis. While one strand can be copied all the way to the end of a chromosome, the other, lagging strand, must be primed at short intervals in order to provide a 3 OH group for DNA polymerase as the replication fork advances through a chromosome. The problem at the end of a chromosome then is that the lagging strand has nothing for the primer to bind to. Without some kind of solution, each replication cycle would result in a shorter chromosome. ....

Elizabeth Blackburn , Carol Greider , Jack Szostak , End Nobel Lecture Angewandte Chemie International Edition , Nucleic Acids Research , National Science Foundation , Nobel Prize , Tetrahymena Journal , Molecular Biology , Nobel Lecture , Angewandte Chemie International Edition , Structural Basis , Holoenzyme La Family Protein , Molecule World , National Science , எலிசபெத் கருப்பட்டி , கரோல் கிரேடர் , பலா ஸ்ஜோஸ்த்தக் , தேசிய அறிவியல் அடித்தளம் , நோபல் ப்ரைஸ் , மூலக்கூறு உயிரியல் , நோபல் சொற்பொழிவு , கட்டமைப்பு அடிப்படையில் , மூலக்கூறு உலகம் , தேசிய அறிவியல் ,

14 new professors appointed

At its meeting of 9 and 10 December 2020 and upon application of Joël Mesot, President of ETH Zurich, the ETH Board appointed 14 professors. They will work in a total of ten departments in a wide range of research areas. In addition, an ecotoxicologist was awarded the title of professor.
The new professors in brief:
Dr Pierrick Bousseau ( 1992), currently CNRS Research Fellow at the University of Paris-Saclay, France, as Assistant Professor of Mathematical Physics in the Department of Mathematics. Pierrick Bousseau conducts research in an area where algebraic geometry intersects with mathematical physics and symplectic geometry. He has a particular interest in enumerative geometry, which is concerned with counting geometric objects with given characteristics. Pierrick Bousseau has won several awards for his research. By appointing him, the Department of Mathematics is gaining a talented young mathematician with strong links to theoretical physics. ....

France General , United States , United Kingdom , Benjamin Dillenburger , Bjarne Steffen , Kristin Schirmer , Volodymyrm Korkhov , Theodoros Rekatsina , Patrick Steinegger , Theodoros Rekatsinas , Rachel Grange , Jordon Hemingway , Dominik Hangartner , Annalisa Manera , Elizabeth Tilley , Kathrin Lang , Pierrick Bousseau , Joaquim Serra , Judit Szul , Professor Of Development Engineering , University Of Malawi , Political Sciences , University Of Michigan , National Centre Of Competence , Technical University Of Munich , European Mathematical Society ,