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Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for DENV infection using IgM, IgG and qPCR assay; where 76 samples were positive for DENV and analysed for twelve inflammatory cytokines using ELISA. Serotyping shows 14 DENV-1, 22 DENV-2, 7 DENV-3 and 33 DENV-4, where DENV-4 was predominant. Among seventy-six, forty-two isolates were successfully sequenced for C-prM region and grouped. A lineage shift was observed in DENV-4 genotype. Irrespective of serotypes, IFNγ was significantly elevated than control and in primary infection indicating its ro ....
Impacto potencial de la candidata a vacuna contra el dengue de Takeda, reforzado por los resultados de seguridad a largo plazo y eficacia yahoo.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from yahoo.com Daily Mail and Mail on Sunday newspapers.
7-yr-old dengue patient dies, Gurugram hospital billed parents Rs 16 lakh; Nadda orders probe He Claimed That Gurugram s Fortis Hospital Charged Them Of Rs 16 Lakh For 15-day Dengue Treatment Of Their Daughter Who Later Succumbed To The Disease. News Nation Bureau | Edited By : Vikas Mehta | Updated on: 21 Nov 2017, 01:29:08 PM New Delhi: Union Health Minister J P Nadda on Monday asked members of a patient, who reportedly died of dengue recently, to send all details to his ministry as serious allegations were levelled against a Gurgaon-based private hospital of overcharging the victim. Nadda has also asked Health Secretary to probe the matter. ....
Takeda Begins Regulatory Submissions for Dengue Vaccine Candidate in EU and Dengue-Endemic Countries asiaone.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from asiaone.com Daily Mail and Mail on Sunday newspapers.