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Can Light Microscopy be Used to Visualize Viruses?


Image Credit: Likoper/Shutterstock.com
L’occhio Della Mosca (
The Fly’s Eye) by Giambattista Odierna in 1644 CE. In that sensational book, the Italian naturalist provided the first detailed account of organic tissue – enabled by studying organic matter under the lens of newly invented microscopes. Now, the latest optical microscope technology is capable of imaging viruses that live in organisms.
Conventional Light Microscopes: Widefield and Confocal
Conventional light microscopes – widefield and confocal optical microscopes – can accurately depict image samples at resolutions of around 230 nm (widefield) or 180 nm (confocal) in the XY axes. On the Z-axis (analogous to focal length in photography), these traditional microscopy methods work at resolutions of around 1000 nm (widefield) or 500 nm (confocal). ....

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Biodegradable Nanoprobes Improve Cancer Diagnosis


Biodegradable Nanoprobes Improve Cancer Diagnosis
Written by AZoNanoMar 12 2021
New nanoprobes, which were recently developed by Imperial College London (ICL) and tested in zebrafish, could help identify cancer more precisely and may support the diagnosis and treatment in the days to come.
Purple cancer cells are labeled using bioharmonophores (white label). Image Credit: Imperial College London.
To clearly visualize tumors in the body for cancer diagnosis, physicians can utilize miniature optical probes (nanoprobes) that illuminate upon binding to tumors. Such nanoprobes enable doctors to detect the size, shape and location of tumors in the body.
The majority of the nanoprobes are fluorescent, which means they absorb light of a particular color, such as blue, and then produce a background light of a different color, such as green. ....

City Of , United Kingdom , Periklis Pantazis , Royal Society , College London Imperial , Imperial College London , European Union , Swiss National Science Foundation , Swiss National Centre Of Competence , Image Credit , Imperial College , Lead Researcher , Light Microscopy , Wellcome Trust , Swiss National Centre , Biodegradable Harmonophores , Targeted High Resolution In Vivo Tumor , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , அரச சமூகம் , கல்லூரி லண்டன் ஏகாதிபத்தியம் , ஏகாதிபத்தியம் கல்லூரி லண்டன் , ஐரோப்பிய தொழிற்சங்கம் , சுவிஸ் தேசிய அறிவியல் அடித்தளம் , சுவிஸ் தேசிய மையம் ஆஃப் திறன் , படம் கடன் ,