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Mapping the cellular circuits behind spitting

Mapping the cellular circuits behind spitting
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Davidh kochH robert horvitzNikhil bhatlaMcgovern institute for brain researchKoch institute for integrative cancer researchHoward hughes medical institute investigatorSteve sando phdMcgovern instituteBrain researchKoch instituteIntegrative cancer researchTasting lightஏச் ராபர்ட் ஹார்விட்ஸ்மகவர்ந் நிறுவனம் க்கு மூளை ஆராய்ச்சிகோச் நிறுவனம் க்கு ஒருங்கிணைந்த புற்றுநோய் ஆராய்ச்சிஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் புலனாய்வாளர்

Expelling cancer by squeezing out rogue cells

May 5, 2021 11:00am MIT biologists reported that the cell elimination process called cell extrusion could offer new insights into stopping cancer. (Vivek Dwivedi) Cancer cells multiply out of control because they re able to escape a mechanism known as programed cell death. But scientists at the Massachusetts Institute of Technology (MIT) and King’s College London have uncovered key functions of another pathway with a long evolutionary history that the body uses to dispose of those rogue cells. During this process, called cell extrusion, cells are squeezed out of the lining of tissues. The team, led by Nobel laureate H. Robert Horvitz, Ph.D., found that the process is triggered when cells fail to replicate their DNA during cell division, according to a study published in Nature.

City ofUnited kingdomVivek dwivediH robert horvitzKing college londonMassachusetts institute of technologyVanderbilt universityMassachusetts instituteCollege londonKing 039s college londonCell deathCell divisionAcademic researchநகரம் ஆஃப்ஒன்றுபட்டது கிஂக்டம்விவேக் டுவிவேடி

Biologists discover a trigger for cell extrusion

MIT biologists find cell extrusion, a process that helps organisms eliminated unneeded cells, is triggered when cells can’t replicate their DNA during cell division. In humans, extrusion may serve as a way for the body to eliminate cancerous or precancerous cells.

City ofUnited kingdomJody rosenblattDavidh kochVivek dwivediNolan tuckerH robert horvitzCarlos pardoDaniel denningRita drosteKing college londonMcgovern institute for brain researchKoch institute for integrative cancer researchNational institutes of healthHoward hughes medical instituteMcgovern institute

Eyeless roundworms sense color - ScienceBlog com

Eyeless roundworms sense color March 5, 2021MIT Roundworms don’t have eyes or the light-absorbing molecules required to see. Yet, new research shows they can somehow sense color. The study, published on March 5 in the journal Science, suggests worms use this ability to assess the risk of feasting on potentially dangerous bacteria that secrete blue toxins. The researchers pinpointed two genes that contribute to this spectral sensitivity and are conserved across many organisms, including humans. “It’s amazing to me that a tiny worm with neither eyes nor the molecular machinery used by eyes to detect colors can identify and avoid a toxic bacterium based, in part, on its blue color,” says H. Robert Horvitz, the David H. Koch Professor of Biology at MIT, a member of the McGovern Institute for Brain Research and the Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute Investigator, and the co-senior author of the study. “One of the joys of bei

Robin chemers neusteinDipon ghoshDavidh kochLeslie vosshallH robert horvitzMcgovern institute for brain researchKoch institute for integrative cancer researchRockefeller universityHoward hughes medical institute investigatorNational instituteHoward hughes medical instituteMcgovern instituteBrain researchKoch instituteIntegrative cancer researchRobin chemers neustein professor

Stuart Orkin receives $500,000 Gruber Genetics Prize for his groundbreaking research on genetics of inherited blood disorders

Stuart Orkin receives $500,000 Gruber Genetics Prize for his groundbreaking research on genetics of inherited blood disorders
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United statesUnited kingdomMary claire kingEmmanuelle charpentierDavid baulcombeGary ruvkunDouglasc wallaceVictor ambrosEric olsonRoberth waterstonStephen elledgeBert vogelsteinElizabethh blackburnAllan spradlingBonnie basslerH robert horvitz