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News Scan for Jul 01, 2021


The global prevalence of vancomycin-resistant
Staphylococcus aureus (VRSA) has more than tripled in the past two decades, according to a systematic review and meta-analysis yesterday in
Antimicrobial Resistance & Infection Control.
The review of 62 published studies on VRSA prevalence rates, conducted by a team of Chinese and Iranian researchers, found that prevalence increased from 2% of 466 isolates before 2006 to 6% of 6,692 isolates from 2006 through 2014 and 7% of 5,798 isolates from 2015 through 2020.  Prevalence was highest in Africa (16%) and Asia (5%), followed by North America (4%), South America (3%), and Europe (1%). The frequencies of VRSA isolates from clinical, non-clinical, and mixed samples were 6%, 7%, and 14%, respectively.
Analysis of the genetic backgrounds of VRSA strains found that 71% and 26% were positive for ....

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News Scan for May 11, 2021


S aureus isolates were methicillin-resistant, 34% of
Enterococcus faecium were resistant to vancomycin, and 58% of
Streptococcus pneumoniae had reduced susceptibility to penicillin.
Among gram-negative bacteria, 59% of
E coli and 40% of
K pneumoniae produced extended-spectrum beta-lactamase (ESBL) enzymes, and 29% and 11% were resistant to carbapenems, respectively. In addition, 79% of
Acinetobacter spp. and 45% of
Pseudomonas aeruginosa were carbapenem resistant, and 88% of
Haemophilus influenzae were resistant to ampicillin.
When compared with data collected from the same hospitals in 2012-13, the proportion  of antibiotic-resistant isolates were higher in 2016-17 for most pathogen-antibiotic combinations of interest, including imipenem-resistant
A baumannii,
E coli,
P aeruginosa was also higher. ....

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[Full text] Antibiotic Susceptibility Patterns of Bacterial Isolates from Routine


2Central Tuberculosis Reference Laboratory (CTRL), Dar es Salaam, Tanzania;
3School of Life Science and Bioengineering, Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania;
4University of Saskatchewan, Saskatoon, Canada;
5Department of Epidemiology and Statistics, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania
Correspondence: Nicholaus P Mnyambwa
Email [email protected]
Introduction: Antimicrobial resistance is one of the biggest threats of modern public health. Although sub-Saharan Africa is highly burdened with infectious diseases, current data on antimicrobial resistance are sparse.
Methods: A prospective study was conducted between October 2018 and September 2019 to assess the antibiotic susceptibility patterns of clinical bacterial isolates obtained from four referral hospitals in Tanzania. We used standard media and Kirby-Bauer disc diffusion methods as per Clinical and Laboratory Standar ....

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