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Large-scale drug analysis reveals potential new COVID-19 antivirals

Large-scale drug analysis reveals potential new COVID-19 antivirals
ANI |
Updated: Jul 04, 2021 08:14 IST
London [UK], July 4 (ANI): Researchers at the Francis Crick Institute and University of Dundee have screened thousands of drug and chemical molecules and identified a range of potential antivirals that could be developed into new treatments for COVID-19 or in preparation for future coronavirus outbreaks.
In a series of seven papers, published in the Biochemical Journal, the scientists identified 15 molecules that inhibit the growth of SARS-CoV-2 by blocking different enzymes involved in its replication.
While COVID-19 vaccines are being rolled out, there are still few drug options that can be used to treat patients with the virus, reduce symptoms and speed up recovery time. These treatments are especially important for groups where the vaccines are less effective, such as some patients with blood cancers. ....

City Of , United Kingdom , John Diffley , Francis Crick Institute , Chromosome Replication Laboratory , University Of Dundee , Biochemical Journal , High Throughput Screening , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , ஜான் டிஃப்லி , பிரான்சிஸ் கிரிக் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் டண்டீ , உயிர்வேதியியல் இதழ் ,

Potential COVID-19 antivirals discovered

Potential COVID-19 antivirals discovered
04 Jul 2021, 13:03 GMT+10
London [UK], July 4 (ANI): Researchers at the Francis Crick Institute and University of Dundee have screened thousands of drug and chemical molecules and identified a range of potential antivirals that could be developed into new treatments for COVID-19 or in preparation for future coronavirus outbreaks.
In a series of seven papers, published in the Biochemical Journal, the scientists identified 15 molecules that inhibit the growth of SARS-CoV-2 by blocking different enzymes involved in its replication.
While COVID-19 vaccines are being rolled out, there are still few drug options that can be used to treat patients with the virus, reduce symptoms and speed up recovery time. These treatments are especially important for groups where the vaccines are less effective, such as some patients with blood cancers. ....

City Of , United Kingdom , John Diffley , Francis Crick Institute , Chromosome Replication Laboratory , University Of Dundee , Biochemical Journal , High Throughput Screening , நகரம் ஆஃப் , ஒன்றுபட்டது கிஂக்டம் , ஜான் டிஃப்லி , பிரான்சிஸ் கிரிக் நிறுவனம் , பல்கலைக்கழகம் ஆஃப் டண்டீ , உயிர்வேதியியல் இதழ் ,

Large-scale drug analysis reveals potential new COVID-19 antivirals

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Researchers at the Francis Crick Institute and University of Dundee have screened thousands of drug and chemical molecules and identified a range of potential antivirals that could be developed into new treatments for COVID-19 or in preparation for future coronavirus outbreaks.
While COVID-19 vaccines are being rolled out, there are still few drug options that can be used to treat patients with the virus, to reduce symptoms and speed up recovery time. These treatments are especially important for groups where the vaccines are less effective, such as some patients with blood cancers.
In a series of seven papers, published today (2 July) in the ....

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Technology that predicts protein stability is released by UK university spin-out company

A digital tool that will make it cheaper, safer and faster to develop new medicines is being rolled out by scientists from the University of Bath in the UK. ....

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George David Dickinson

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Presenilin-null cells have altered two-pore calcium channel expression and lysosomal calcium: implications for lysosomal function, Brain Research
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The Probability of Triggering Calcium Puffs Is Linearly Related to the Number of Inositol Trisphosphate Receptors in a Cluster, Biophysical Journal
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Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels, Journal of Biological Chemistry
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Deviant nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated Ca2+ signaling upon lysosome proliferation, Journal of Biological Chemistry
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Modulation of NAADP (nicotinic acid-adenine dinucleotide phospha ....

United States , University College , New South Wales , University College London , University Of California , Nature Communications , Doctoral Research Scientist In Materials Science , Brain Research , University Of Aberdeen , Boise State University , Proceedings Of The National Academy Sciences , University Of York , Idaho Bureau Of Laboratoriesor , Doctoral Research Scientist , Materials Science , Sound Science , Idaho Bureau , Project Scientist , Cell Calcium , Science Signalling , Biophysical Journal , Triggering Calcium Puffs Is Linearly Related , Inositol Trisphosphate Receptors , Biological Chemistry , Biochemical Journal , National Academy ,