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LIM domain only 1: One gene, many roles in cancer


IMAGE: In a new article in
Chinese Medical Journal, researchers have reviewed studies detailing molecular features of the gene LIM domain only 1, whose coded protein has a role in tumor.
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Credit:
Chinese Medical Journal
Humans have been plagued by a myriad of deadly cancers since ages. Parallelly, they have also been attempting different permutations and combinations of treatments to cure the disease. Part of these attempts involving biomolecular targets have come to the fore in recent years. Like a broad-spectrum antibiotic that can attack and eliminate several microbes at a time, some of these biomolecular targets, when manipulated appropriately, can alleviate different cancers. One such biomolecular target of interest is LIM domain only 1 gene (LMO1). ....

Chao Jia , United States , Texas State University In United States , Hospital Of Hebei University , Affiliated Hospital , Hebei University , Texas State University , Chinese Medical , Professor You Chao Jia , Professor Jia , Cell Biology , Medicine Health , Clinical Trials , Gene Therapy , ஒன்றுபட்டது மாநிலங்களில் , இணைந்த மருத்துவமனை , டெக்சாஸ் நிலை பல்கலைக்கழகம் , சீன மருத்துவ , ப்ரொஃபெஸர் ஜியா ,

Study on plant roots challenges nature of ecological trade-offs

A volcanic eruption 39 million years ago buried a forest in Peru – now the petrified trees are revealing South America's primeval history


In the hills outside the small village of Sexi, Peru, a fossil forest holds secrets about South America’s past millions of years ago.
When we first visited these petrified trees more than 20 years ago, not much was known about their age or how they came to be preserved. We started by dating the rocks and studying the volcanic processes that preserved the fossils. From there, we began to piece together the story of the forest, starting from the day 39 million years ago when a volcano erupted in northern Peru.
Ash rained down on the forest that day, stripping leaves from the trees. Then flows of ashy material moved through, breaking off the trees and carrying them like logs in a river to the area where they were buried and preserved. Millions of years later, after the modern-day Andes rose and carried the fossils with them, the rocks were exposed to the forces of erosion, and the fossil woods and leaves again saw the light of day. ....

United States , Florissant Fossil Beds National Monument , Mariah Slovacek , Petrifed Forest National Park , National Park Service , Mariah Slovacek National Park Service , South America , South American , New World , South America , ஒன்றுபட்டது மாநிலங்களில் , புளோரிசண்ட் தொல்பொருள் படுக்கைகள் தேசிய நினைவுச்சின்னம் , தேசிய பூங்கா சேவை , தெற்கு அமெரிக்கா , தெற்கு அமெரிக்கன் , புதியது உலகம் ,

Meiosis: Mind the gap


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IMAGE: Scientists have now discovered that cells sometimes liberate DNA fragments at sites of paired, or double, DSBs.
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Credit: © Franz Klein, Chromosomenbiologie, Universität Wien
Scientists from the lab of Franz Klein from the Department of Chromosome Biology at the Max Perutz Labs, a joint venture of the University of Vienna and the Medical University of Vienna, have now discovered that cells sometimes liberate DNA fragments at sites of paired, or double, DSBs. Whilst this presents an obvious risk of germline mutations as a consequence of erroneous repair or of integration of fragments from elsewhere at break sites, it may also be a source of evolutionary diversity. The study is published as a research article in ....

Franz Klein , Silvia Prieler , Doris Chen , Department Of Chromosome Biology , University Of Vienna , Chromosome Biology , Max Perutz Labs , Medical University , Cell Biology , Medicine Health , ஃப்ரான்ஸ் க்ளீன் , டோரிஸ் சென் , பல்கலைக்கழகம் ஆஃப் வியன்னா , குரோமோசோம் உயிரியல் , மருத்துவ பல்கலைக்கழகம் ,