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Frontiers | Emergence of Dengue 4 as Dominant Serotype During 2017 Outbreak in South India and Associated Cytokine Expression Profile

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for DENV infection using IgM, IgG and qPCR assay; where 76 samples were positive for DENV and analysed for twelve inflammatory cytokines using ELISA. Serotyping shows 14 DENV-1, 22 DENV-2, 7 DENV-3 and 33 DENV-4, where DENV-4 was predominant. Among seventy-six, forty-two isolates were successfully sequenced for C-prM region and grouped. A lineage shift was observed in DENV-4 genotype. Irrespective of serotypes, IFNγ was significantly elevated than control and in primary infection indicating its ro

India
Australia
Koishi
Hokkaido
Japan
Taiwan
United-states
United-kingdom
New-delhi
Delhi
Brazil
Pune

Water security, climate change, global warming, arsenic | Homeland Security Newswire

Water security, climate change, global warming, arsenic | Homeland Security Newswire
homelandsecuritynewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from homelandsecuritynewswire.com Daily Mail and Mail on Sunday newspapers.

Maine
United-states
Texas
Alaska
California
Indiana
Ohio
Michigan
America
Melissa-lombard
Centers-for-disease
Us-environmental-protection-agency

CVIA has just published a new issue, Volume 5 Issue 3

CVIA has just published a new issue, Volume 5 Issue 3
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Yao-dong
Guangdong
China
Jing-li
Henan
United-states
Yu-zhang
Zhejiang
Yuan-ding
Fujian
Beijing
Yuan-li

Sydney Lockdown Extended; Pope Makes Vaccine Plea: Virus Update

Mutant Strain Spreads; N.J. Records Worst Month: Virus Update Bloomberg 12/26/2020 (Bloomberg) U.S. cases rose on Christmas Day at the slowest rate in almost two months, though the numbers were likely skewed by the holiday. Hospitalizations in New York City continued to climb, while statewide the total fell slightly, as did new infections. New Jersey has had about as many cases in December as it did from May through October. North Carolina surpassed 500,000 infections over the holiday. Japan will ban entry to most non-Japanese nationals through the end of January. Global infections surpassed 80 million. As some European Union nations began vaccinations, Sweden joined France, Germany, Switzerland, Ireland and Japan on a growing list of countries that have identified their first cases of the coronavirus mutation widespread in the U.K. The Canadian province of Ontario said it also identified two cases not apparently tied to travel.

Japan
California
United-states
France
New-york
Saudi-arabia
Rome
Lazio
Italy
Ireland
University-of-zambia
Lusaka

Pope Makes Vaccine Plea; NYC Hospitalizations Rise: Virus Update

Mutant Strain Spreads; N.J. Records Worst Month: Virus Update Bloomberg 12/26/2020 (Bloomberg) U.S. cases rose on Christmas Day at the slowest rate in almost two months, though the numbers were likely skewed by the holiday. Hospitalizations in New York City continued to climb, while statewide the total fell slightly, as did new infections. New Jersey has had about as many cases in December as it did from May through October. North Carolina surpassed 500,000 infections over the holiday. Japan will ban entry to most non-Japanese nationals through the end of January. Global infections surpassed 80 million. As some European Union nations began vaccinations, Sweden joined France, Germany, Switzerland, Ireland and Japan on a growing list of countries that have identified their first cases of the coronavirus mutation widespread in the U.K. The Canadian province of Ontario said it also identified two cases not apparently tied to travel.

Japan
California
United-states
France
New-york
Saudi-arabia
Rome
Lazio
Italy
Ireland
Hong-kong
Lusaka

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