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Frontiers | Excitatory Repetitive Transcranial Magnetic Stimulation Over Prefrontal Cortex in a Guinea Pig Model Ameliorates Tinnitus


2School of Biological Sciences, University of Western Australia, Crawley, WA, Australia
3Perron Institute for Neurological and Translational Research, Crawley, WA, Australia
Tinnitus, a phantom auditory perception that can seriously affect quality of life, is generally triggered by cochlear trauma and associated with aberrant activity throughout the auditory pathways, often referred to as hyperactivity. Studies suggest that non-auditory structures, such as prefrontal cortex (PFC), may be involved in tinnitus generation, by affecting sensory gating in auditory thalamus, allowing hyperactivity to reach the cortex and lead to perception. Indeed, human studies have shown that repetitive transcranial magnetic stimulation (rTMS) of PFC can alleviate tinnitus. The current study investigated whether this therapeutic effect is achieved through inhibition of thalamic hyperactivity, comparing effects of two common clinical rTMS protocols with sham treatment, in a guinea pig tinnitus ....

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Antiviral drug 'Clevira' repurposed for treatment of mild to moderate COVID-19 cases


Antiviral drug Clevira repurposed for treatment of mild to moderate COVID-19 cases
Photo: Pexels
Clevira, a drug primarily developed to treat dengue, has been repurposed as supportive treatment for mild to moderate COVID-19 cases, its manufacturer Apex Laboratories Private Limited said on Friday.
The drug is effective when taken orally and the dosage is one tablet twice daily after food for 14 days. The drug has also proved to be safe on liver and kidney parameters, it said.
Clevira, an antiviral formulation, has received regulatory approval as a supportive treatment for mild to moderate COVID-19 cases, the Chennai-based pharmaceutical company said. ....

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oxygen generators: Covid-19: Japan to provide 300 oxygen concentrators, ventilators to India, Health News, ET HealthWorld

oxygen generators: Covid-19: Japan to provide 300 oxygen concentrators, ventilators to India, Health News, ET HealthWorld
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