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UTMB researchers receive $11.3 million grant to study immunopathogenesis of Ebola

UTMB researchers receive $11.3 million grant to study immunopathogenesis of Ebola
Researchers at the University of Texas Medical Branch at Galveston have been awarded an $11.3 Million, multi-year grant from the National Institute of Allergy and Infectious Diseases to study immunopathogenesis of Ebola, and in particular to determine why cells infected with Ebola develop immune system paralysis, which inhibits immune response, leads to hyperinflammation, and allows the deadly infection to spread. The research will be led by Co-Principal Investigators Alexander Bukreyev, PhD, of UTMB s Department of Pathology, and Mariano Garcia-Blanco, MD, PhD, Chair of the Biochemistry and Molecular Biology Department.
While some might question, Why Ebola now? Dr. Bukreyev explains that, while the COVID-19 pandemic has grabbed headlines and been a primary focus for researchers worldwide for the last 18 months, scientists at UTMB have never stopped working to increase their understanding ....

United States , Thomas Geisbert , Matt Weirauch , Alexander Bukreyev , Stuart Sealfon , Ricardo Rajsbaum , Ivan Marazzi , Mariano Garcia Blanco , Emily Henderson , Andrew Routh , Molecular Biology Department , National Institute Of Allergy , World Health Organization , Department Of Microbiology Immunology , Department Of Biochemistry , Galveston National Laboratory , University Of Texas Medical Branch At Galveston , Department Of Pathology , Texas Medical Branch , National Institute , Infectious Diseases , Co Principal Investigators Alexander Bukreyev , Molecular Biology , Co Principal Investigator , Biosafety Level , Galveston National ,

UTMB scientists awarded $11.3 million for new studies on Ebola virus

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GALVESTON, TEXAS - Researchers at the University of Texas Medical Branch at Galveston have been awarded an $11.3 Million, multi-year grant from the National Institute of Allergy and Infectious Diseases to study immunopathogenesis of Ebola, and in particular to determine why cells infected with Ebola develop immune system paralysis, which inhibits immune response, leads to hyperinflammation, and allows the deadly infection to spread. The research will be led by Co-Principal Investigators Alexander Bukreyev, PhD, of UTMB s Department of Pathology, and Mariano Garcia-Blanco, MD, PhD, Chair of the Biochemistry and Molecular Biology Department.
While some might question, Why Ebola now? Dr. Bukreyev explains that, while the COVID-19 pandemic has grabbed headlines and been a primary focus for researchers worldwide for the last 18 months, scientists at UTMB have never stopped working to increase their understanding of Ebola as part of a global effort to develop effect ....

United States , University Of Texas , Thomas Geisbert , Matt Weirauch , Alexander Bukreyev , Stuart Sealfon , Ricardo Rajsbaum , Ivan Marazzi , Mariano Garcia Blanco , Andrew Routh , Molecular Biology Department , National Institute Of Allergy , World Health Organization , Department Of Microbiology Immunology , Department Of Biochemistry , Galveston National Laboratory , University Of Texas Medical Branch At Galveston , Department Of Pathology , Texas Medical Branch , National Institute , Infectious Diseases , Co Principal Investigators Alexander Bukreyev , Molecular Biology , Biosafety Level , Galveston National , Icahn School ,

Cancer drug may be able to treat inflammation caused by COVID-19 virus: Singapore-US study

Cancer drug may be able to treat inflammation caused by COVID-19 virus: Singapore-US study
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Cancer drug may be able to treat inflammation caused by COVID-19 virus: Singapore-US study
Dr Anand Jeyasekharan with a vial of Topotecan, a cancer drug that could potentially be used in the treatment of COVID-19. (Photo: National University Cancer Institute, Singapore)
07 Apr 2021 09:50PM)
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SINGAPORE: A widely available and inexpensive drug used for cancer treatment could potentially be used in the treatment of COVID-19, according to a study by Singapore and US researchers.
They found that the chemotherapeutic drug, called Topotecan, reduced the severity and death rates of infection by the virus that causes COVID-19, by suppressing inflammation in the lungs of laboratory animals. ....

United States , Hong Kong , United Kingdom , Anand Jeyasekharan , Ivan Marazzi , National Research Foundation , National University Cancer Institute , Icahn School Of Medicine At Mount Sinai , Department Of Haematology , Research Fund , Microbiology Department , Icahn School , Mount Sinai , Singapore Ministry , National Medical Research Council , Medical Oncology , Professor Ivan Marazzi , ஒன்றுபட்டது மாநிலங்களில் , ஹாங் காங் , ஒன்றுபட்டது கிஂக்டம் , ஆனந்த் ஜெயசேகரன் , இவன் மராஸி , தேசிய ஆராய்ச்சி அடித்தளம் , தேசிய பல்கலைக்கழகம் புற்றுநோய் நிறுவனம் , இக்ஹ்ன் பள்ளி ஆஃப் மருந்து இல் ஏற்ற சினை , துறை ஆஃப் ஹீமாட்டாலஜி ,

Even after late start, anti-inflammatory drug protects against lethal inflammation from COVID

Even after late start, anti-inflammatory drug protects against lethal inflammation from COVID
scienceblog.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from scienceblog.com Daily Mail and Mail on Sunday newspapers.

United States , Hong Kong , United Kingdom , Mikhail Spivakov , Jessica Sook Yuin , Ivan Marazzi , National Medical Research Council Of Singapore , Icahn School Of Medicine At Mount Sinai , World Health Organization , London Institute Of Medical Sciences , Mount Sinai , Associate Professor , Icahn School , Icahn Mount , Functional Gene Control , Medical Sciences , National Medical Research Council , ஒன்றுபட்டது மாநிலங்களில் , ஹாங் காங் , ஒன்றுபட்டது கிஂக்டம் , ஜெசிகா அதனால் சரி யூய்ன் , இவன் மராஸி , தேசிய மருத்துவ ஆராய்ச்சி சபை ஆஃப் சிங்கப்பூர் , இக்ஹ்ன் பள்ளி ஆஃப் மருந்து இல் ஏற்ற சினை , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , லண்டன் நிறுவனம் ஆஃப் மருத்துவ அறிவியல் ,

Drug protects against COVID-19 inflammation in pre-clinical trials

Drug protects against COVID-19 inflammation in pre-clinical trials
drugtargetreview.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from drugtargetreview.com Daily Mail and Mail on Sunday newspapers.

United Kingdom , Mikhail Spivakov , Jessica Sook Yuin , Ivan Marazzi , Mount Sinai School Of Medicine , London Institute Of Medical Sciences , Drug Administration , Research Council , Mount Sinai Hospital , Mount Sinai School , Associate Professor Ivan , Medical Research Council , London Institute , Medical Sciences , ஒன்றுபட்டது கிஂக்டம் , ஜெசிகா அதனால் சரி யூய்ன் , இவன் மராஸி , ஏற்ற சினை பள்ளி ஆஃப் மருந்து , லண்டன் நிறுவனம் ஆஃப் மருத்துவ அறிவியல் , ஆராய்ச்சி சபை , ஏற்ற சினை மருத்துவமனை , ஏற்ற சினை பள்ளி , மருத்துவ ஆராய்ச்சி சபை , லண்டன் நிறுவனம் , மருத்துவ அறிவியல் ,