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20 years after the discovery of the human genome, dangerous gene myths abound | Philip Ball


Misleading rhetoric has fuelled the belief that our genetic code is an ‘instruction book’ – but it’s far more interesting than that
‘Successes in gene therapy remain rare, and medicine tailored to people’s individual genetic constitution has not yet materialised.’ Photograph: Alamy
‘Successes in gene therapy remain rare, and medicine tailored to people’s individual genetic constitution has not yet materialised.’ Photograph: Alamy
Wed 9 Jun 2021 06.43 EDT
Last modified on Wed 9 Jun 2021 06.45 EDT
Twenty years ago, the science journal Nature published the first draft of the human genome: the sequence of chemical “letters” on the gene-bearing DNA of our chromosomes. The Human Genome Project (HGP) had laboured for a decade to read this coded information. In a White House press conference in 2000, Francis Collins, , who led the project as director of the US National Human Genome Research Institute, waxed biblical, calling the human genome “ ....

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More Fun Than Fun: The Joys and Burdens of Our Heroes


More Fun Than Fun: The Joys and Burdens of Our Heroes
12/05/2021
Among the books I read as a teenager, two completely changed my life. One was
The Double Helix by Nobel laureate James D. Watson. This book was inspiring at many levels and instantly got me addicted to molecular biology. The other was
King Solomon’s Ring by Konrad Lorenz, soon to be a Nobel laureate. The study of animal behaviour so charmingly and unforgettably described by Lorenz kindled in me an eternal love for the subject.
The circumstances in which I read these two books are etched in my mind and may have partly contributed to my enthusiasm for them and their subjects. ....

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Book Review: The Code Breaker


You know how writers are sometimes asked whom they would like to have over for a small dinner party? Well, historian, biographer and academic Walter Isaacson, out now with another magnificent tome,
The Code Breaker, says – with nods to other innovators he’s written about, including Einstein, Steve Jobs and his favorite genius, Leonardo Da Vinci – that his guests would be Benjamin Franklin and Jennifer Doudna.
Franklin, whom Isaacson wrote about in 2003, was a prime exemplar of “curiosity,” the driving force behind inquiries and inventions.
As for Doudna, who he says manifests the same kind of obsessive inquisitiveness about nature as Franklin, her name emerged for most of us only last fall along with that of Emmanuelle Charpentier. They shared the 2020 Nobel Prize for chemistry, having helped pioneer CRISPR, a gene editing technique, using tracer RNA to direct DNA to recognize and fight viruses that attack bacteria. ....

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