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Texas bans local mask mandates; South Africa registers...


Singapore, reeling from a new wave of infections that has forced a return to lockdowns, will lengthen the time between vaccination doses to stretch out supply. The city-state will also authorise the Pfizer shot for children as young as 12.
Combining doses of vaccines from AstraZeneca and Pfizer is safe and gives people high levels of immunity, according to a study by Spain’s Instituto de Salud Carlos III. The research institution conducted one of the first studies into the combined use of shots that includes clinical trials.
Britain will approve Johnson & Johnson’s one-dose vaccine “very imminently,” according to the UK drugs regulator. In the US, Texas banned local governments and schools from mandating mask-wearing. ....

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Inhibition of proteins activated by nitric oxide reverses aortic aneurysm in Marfan syndrome


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IMAGE: Sara Martínez Martínez, María José Méndez Olivares, Álvaro Alfayate, , Andrea de la Fuente-Alonso, Miguel R. Campanero, Juan Miguel Redondo y Jesús Vázquez...
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Credit: CNIC
Scientists at the Centro Nacional de Investigaciones Cardiovasculares Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM) have discovered that the nitric oxide (NO) pathway is overactivated in the aortas of mice and patients with Marfan Syndrome and that the activity of this pathway causes the aortic aneurysms that characterize this disease.
The results of the study, published today in
Nature Communications, reveal the essential role played by NO in Marfan Syndrome aortic disease and identify new therapeutic targets and markers of NO pathway activation that could be used to monitor disease status and progression. ....

Andrea De , Israel General , Juan Miguel Redondo , Marfan Syndrom , Miguel Campanero , Salud Carlos , Investigaciones Cardiovasculares Centro , Nature Communications , Marfan Foundation , Caixaresearch Call For Health , Community Of Madrid , Ghent University , Molecular Severo Ochoa , Marfan Syndrome , Andrea De La Fuente Alonso , Marta Toral , Mafan Syndrome , Puerta De Hierro , Caixaresearch Call , Health Projects , Ministerio De Ciencia , Instituto De Salud Carlos , ஆண்ட்ரியா டி , இஸ்ரேல் ஜநரல் , சலுத் கார்லோஸ் , இயற்கை தகவல்தொடர்புகள் ,