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Researchers uncover mechanism related to severe post-COVID-19 disease in children


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BOSTON A multidisciplinary team from MassGeneral Hospital for Children (MGHfC), Brigham and Women s Hospital and other institutions have identified the mechanism of how an extremely rare but serious post-COVID-19 complication develops in children and adolescents. Led by MGHfC pediatric pulmonologist Lael Yonker, MD, researchers determined that viral particles remaining in the gut long after an initial COVID-19 infection can travel into the bloodstream, instigating the condition called Multisystem Inflammatory Syndrome in Children (MIS-C).
The syndrome can occur several weeks after an initial infection; symptoms include high fever, abdominal pain, vomiting, diarrhea, rash and extreme fatigue. The hyperinflammatory response and cytokine storm seen in MIS-C can lead to extensive damage in the heart, liver and other organs. ....

United States , North Carolina , Amos Hostetter , Alessio Fasano , Los Angeles , David Walt , Lael Yonker , Moshe Arditi , National Institute Of Diabetes , Us Centers For Disease , Ragon Institute , European Biomedical Research Institute Of Salerno , Melinda Gates Foundation , University Of Maryland School Medicine , Blood Institute , National Heart , Wyss Institute For Biologically Inspired Engineering , Chieck Foundation , Mghfc Division Of Pediatric Gastroenterology , Sinai Medical Center , National Institutes Of Health , Immunological Diseases Research Center At Cedars , Drug Administration , Department Of Pediatrics , Massgeneral Hospital , Multisystem Inflammatory Syndrome ,

The biggest donors to Wisconsin political parties in 2020


Wausau Pilot & Review
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BY MOLLY LIEBERGALL, THE BADGER PROJECT
A loophole in Wisconsin campaign finance law allows individuals to make unlimited donations to political parties, and also allows political parties to make unlimited donations to candidates. If an individual wants to donate directly to a candidate, there are limits based on state and federal law. But not if they give through a party.
Here’s who is taking advantage of that loophole in Wisconsin, according to campaign finance records.
1. Karla Jurvetson
$2.8 million to the Democratic Party of Wisconsin
A physician, philanthropist, and political activist from Silicon Valley, Karla Jurvetson is divorced from a super-successful tech investor. She has emerged as one of the Democratic Party’s most prolific donors. Of the 41 states that received her support this year, Wisconsin got the largest sum by far, but Arizona, Pennsylvania and other battleground states still received arou ....

United States , San Diego , Manitowish Waters , University Of Wisconsin , Marquette University , Amos Hostetter , Roberte Rubin , Stacey Herzing , Brent Fox , Scott Walker , Robert Price , Paul Growald , Elise Lawson , Joe Biden , Meredith Bluhm Wolf , Wendy Greeney , Kirk Clay , Judy Faulkner , Jennifer Pritzker , Alice Walton , Deborah Kern , Herb Kohl , Lisa Ann Mennet , Lynde Uihlein , David Bonderman , John Charles Miller ,