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Game-Changer for Asymptomatic Alzheimer's Trials?


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Blood tests to screen for amyloid-beta could cut the need for PET scans in half in asymptomatic Alzheimer s research trials, a British cohort study suggested.
To find 100 amyloid PET-positive, dementia-free older adults from a population with similar amyloid PET positivity prevalence to the study cohort without plasma screening, 543 PET scans would need to be performed, said Jonathan Schott, MD, of University College London in England, and co-authors.
Using mass spectrometry measures of plasma amyloid-beta would require 623 people to have a blood test, and of those, 243 would proceed to a scan, they wrote in
To identify Alzheimer s before symptoms, the gold standard tests available right now are amyloid PET scans and lumbar punctures, which are either expensive or relatively invasive, said co-author Ashvini Keshavan, PhD, also of University College London. ....

United Kingdom , Jonathan Schott , Judy George , Ashvini Keshavan , University College London , University College , Medpage Today , ஒன்றுபட்டது கிஂக்டம் , ஜொனாதன் ஸ்காட் , ஜூடி ஜார்ஜ் , அஷ்வினி கேசவன் , பல்கலைக்கழகம் கல்லூரி லண்டன் , பல்கலைக்கழகம் கல்லூரி ,

Dementia care: Blood test may support Alzheimer's treatment


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Dementia is a general term for a cluster of symptoms associated with brain decline. Alzheimer s disease is the most common type of dementia in the UK. Memory loss and lapses in judgement are some of the early signs of Alzheimer s. There is currently no cure for Alzheimer s but identifying its emergence as early as possible could help to forestall it. ....

United Kingdom , Jonathan Schott , Rosa Sancho , Ashvini Keshavan , University College London , Research Council National Survey Of Health , Alzheimer Research United Insight , Prof Jonathan Schott , Medical Research Council National Survey , Getty Images , Privacy Notice , Research United Kingdom Funded Insight , Research United Kingdom , Ctp Video , Autoplay Video , Dementia Care , Alzheimer S , Blood Test , ஒன்றுபட்டது கிஂக்டம் , ஜொனாதன் ஸ்காட் , ரோசா சஞ்சோ , அஷ்வினி கேசவன் , பல்கலைக்கழகம் கல்லூரி லண்டன் , ஆராய்ச்சி சபை தேசிய கணக்கெடுப்பு ஆஃப் ஆரோக்கியம் , முதுமறதி ஆராய்ச்சி ஒன்றுபட்டது நுண்ணறிவு , ப்ரொஃப் ஜொனாதன் ஸ்காட் ,