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Increasingly, origami (the Japanese art of paper folding) is becoming less of an artistic concern and more of a scientific one. The California Institute of Technology made special news in 2006 about a way to weave DNA strands into any two-dimensional shape or figure. Caltech’s Paul Rothemund called it “DNA origami” but that was just the start of it. Image credits: Nikoline Arns. Imagine strands of DNA folded back and forth, forming a scaffold that fills the outline of a desired shape. Then, imagine more DNA strands specially designed to bind to that scaffold. Rothemund, the strand-weaver, explained why this was useful. Scientists would find it easy to create and study any complex nanostructures they might want. Quoted in a 2006 press release, in he said he came up with a half a dozen shapes, including square, triangle, five-pointed star, and smiley face. ....
NIST compiles the first detailed tutorial on DNA origami In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers. Pioneered at the California Institute of Technology in 2006, DNA origami has attracted hundreds of new researchers over the past decade, eager to build receptacles and sensors that could detect and treat disease in the human body, assess the environmental impact of pollutants, and assist in a host of other biological applications. Although the principles of DNA origami are straightforward, the technique s tools and methods for designing new structures are not always easy to grasp and have not been well documented. In addition, scientists new to the method have had no single reference they could turn to for the most efficient way of building DNA structures and how to avoid pitfalls that could waste months or even years o ....
Credit: Pixabay In a technique known as DNA origami, researchers fold long strands of DNA over and over again to construct a variety of tiny 3D structures, including miniature biosensors and drug-delivery containers. Pioneered at the California Institute of Technology in 2006, DNA origami has attracted hundreds of new researchers over the past decade, eager to build receptacles and sensors that could detect and treat disease in the human body, assess the environmental impact of pollutants, and assist in a host of other biological applications. Although the principles of DNA origami are straightforward, the technique’s tools and methods for designing new structures are not always easy to grasp and have not been well documented. In addition, scientists new to the method have had no single reference they could turn to for the most efficient way of building DNA structures and how to avoid pitfalls that could waste months or even years of research. ....