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E-Mail IMAGE: Matthew Foster, MD, and his UNC Lineberger colleagues have used an experimental safety switch incorporated as part of a chimeric antigen receptor-modified T cell therapy (CAR-T) for an aggressive form. view more Credit: UNC Lineberger Comprehensive Cancer Center CHAPEL HILL, North Carolina UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur. This advance was seen in a patient enrolled in a clinical trial using CAR-T to treat refractory acute B-cell leukemia. It demonstrates a proof-of-principle for possible expanded use of CAR-T immunotherapy paired with the safety switch. ....
Posted: Dec 21, 2020 5:00 AM CT | Last Updated: December 21, 2020 On its busiest day of the holidays last year, the Winnipeg James Armstrong Richardson Airport saw about 17,000 passengers. This year, it’s anticipated that number will be about 2,000.(Holly Caruk/CBC) Manitobans are being told to stay home this holiday season, to help prevent the spread of COVID-19. But for many, home is where family is and some are making the journey elsewhere in order to lock down with loved ones. I m going to Toronto to stay with my sister for the holidays, said Judy Willan, who was among the travellers at the Winnipeg James Armstrong Richardson Airport on a recent blustery Monday morning. ....