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Early amcenestrant data featured at ASCO support its potential to become a new endocrine backbone therapy for ER+/HER2- breast cancer

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PARIS, May 19, 2021 /PRNewswire/
Phase 1 data from the AMEERA-1 study evaluating amcenestrant, an investigational oral selective estrogen receptor degrader (SERD), will be presented at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting. In a pooled analysis, amcenestrant in combination with palbociclib showed encouraging antitumor activity in postmenopausal women with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (MBC).
These early clinical data show that the combination of amcenestrant with palbociclib achieved encouraging antitumor activity, said Sarat Chandarlapaty, M.D., Ph.D., Medical Oncologist, Memorial Sloan Kettering Cancer Center. The analysis also demonstrated no clinically significant cardiac or ocular findings and an overall safety profile in line with what we saw in the monotherapy setting. It s notable to see this kind of activity in patients ....

United States , France General , Eva Schaefer Jansen , Arnaud Delepine , Suzanne Greco , Felix Lauscher , John Reed , Sarat Chandarlapaty , Fara Berkowitz , Sally Bain , Global Head Of Research , American Society Of Clinical Oncology , Data Safety Monitoring Committee , Memorial Sloan Kettering Cancer Center , Clinical Oncology , Medical Oncologist , Memorial Sloan Kettering Cancer , Global Head , Empowering Life , Media Relations Contact , Private Securities Litigation Reform Act , Statement Regarding Forward Looking , ஒன்றுபட்டது மாநிலங்களில் , பிரான்ஸ் ஜநரல் , ஈவா ஸ்கேஃபர் ஜான்சன் , ஸுஸ்யாந் க்ரெகொ ,

European Commission approves second indication of Sarclisa® (isatuximab) for relapsed multiple ...

Press release content from Globe Newswire. The AP news staff was not involved in its creation.
European Commission approves second indication of Sarclisa® (isatuximab) for relapsed multiple .
SanofiApril 19, 2021 GMT
European Commission approves second indication of Sarclisa® (isatuximab) for relapsed multiple myeloma
Approval based on Phase 3 IKEMA study demonstrating Sarclisa added to standard of care carfilzomib and dexamethasone reduced risk of disease progression or death by 47% in patients who had relapsed after one to three prior therapies
Sarclisa combination therapy was associated with undetectable levels of multiple myeloma (MM) in nearly 30% of patients with relapsed MM
Second EU approval in less than 12 months for Sarclisa in combination with a standard of care regimen for the treatment of relapsed or refractory MM ....

France General , United States , United Kingdom , South Korea , Eva Schaefer Jansen , Suzanne Greco , Arnaud Delepine , Felix Lauscher , Philippe Moreau , Europe Thephase , Fara Berkowitz , Peterc Adamson , Sally Bain , University Hospital Of Nantes , International Myeloma Foundation , European Commission , Drug Administration , Department Of Hematology , Global Development Head , University Hospital , Pediatric Innovationatsanofi , Safety Profile , Nonproprietary Naming , Biological Products Guidance , Empowering Life , Private Securities Litigation Reform Act ,

Sanofi to invest in a leading-edge production site in Singapore; continues to strengthen its ...

Sanofi to invest in a leading-edge production site in Singapore; continues to strengthen its ...
apnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from apnews.com Daily Mail and Mail on Sunday newspapers.

United States , France General , Eva Schaefer Jansen , Arnaud Delepine , Nicolas Kressmann , Suzanne Greco , Felix Lauscher , Fara Berkowitz , Thomas Triomphe , Sanofi Pasteur , Singapore Economic Development Board , North America , Executive Vice President , Global Head , Empowering Life , ஒன்றுபட்டது மாநிலங்களில் , பிரான்ஸ் ஜநரல் , ஈவா ஸ்கேஃபர் ஜான்சன் , ஸுஸ்யாந் க்ரெகொ , ஃப்யார பெர்கோவிட்ஸ் , தாமஸ் ட்ரியொஂஃப் , சனோஃபி பாஸ்டர் , சிங்கப்பூர் பொருளாதார வளர்ச்சி பலகை , வடக்கு அமெரிக்கா , நிர்வாகி துணை ப்ரெஸிடெஂட் , உலகளாவிய தலை ,

Phase 3 trial of Libtayo® (cemiplimab) monotherapy in advanced cervical cancer stopped early ...

Press release content from Globe Newswire. The AP news staff was not involved in its creation.
Phase 3 trial of Libtayo® (cemiplimab) monotherapy in advanced cervical cancer stopped early .
SanofiMarch 15, 2021 GMT
Phase 3 trial of Libtayo® (cemiplimab) monotherapy in advanced cervical cancer stopped early for positive result on overall survival
Libtayo is the first immunotherapy to demonstrate improved overall survival in patients with cervical cancer, reducing the risk of death by 31% compared to chemotherapy
Trial enrolled patients with advanced cervical cancer regardless of PD-L1 status
Fourth cancer type where Libtayo has positive pivotal data; ....

France General , United Kingdom , United States , South Korea , Eva Schaefer Jansen , Suzanne Greco , Arnaud Delepine , Felix Lauscher , Yvonne Naughton , Vesna Tosic , Fara Berkowitz , Peterc Adamson , Sally Bain , Krishnansus Tewari , Taylor Ramsey , University Of California , Regeneron Genetics Center , European Commission , Data Monitoring Committee , Clinical Sciences , Division Of Gynecologic Oncology , European Union , European Medicines Agency , Libtayo Development Program , Global Development Head , Independent Data Monitoring Committee ,

Sanofi Canada launches Biogenius Grant for high schools, strengthening commitment to equity in the field of STEM learning

/CNW Telbec/ - Addressing the challenge of underfunded public high school science programs and STEM equity across the country, Sanofi Canada is expanding on. ....

Emilija Businskas , Marissa Poole , Sanofi Genzyme , Biogenius Grant , Sanofi Canada , Country Lead , General Manager , Sanofi Biogenius Grant , Sanofi Biogenius Canada , Biogenius Canada , Empowering Life , Media Relations Contact , மரிசா பூல் , சனோஃபி கனடா , நாடு வழி நடத்து , ஜநரல் மேலாளர் , அதிகாரம் வாழ்க்கை , மீடியா உறவுகள் தொடர்பு ,