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Halt cell recycling to treat cancer

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IMAGE: Jun-Lin Guan, PhD, Francis Brunning Professor and Chair of UC s Department of Cancer Biology.
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Credit: University of Cincinnati
Recycling cans and bottles is a good practice. It helps keep the planet clean.
The same is true for recycling within cells in the body. Each cell has a way of cleaning out waste in order to regenerate newer, healthier cells. This cell recycling is called autophagy.
Targeting and changing this process has been linked to helping control or diminish certain cancers. Now, University of Cincinnati researchers have shown that completely halting this process in a very aggressive form of breast cancer may improve outcomes for patients one day. ....

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MedPage Today: Preop chemotherapy misses mark in pancreatic cancer

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MedPage Today: Preop chemotherapy misses mark in pancreatic cancer
Catching pancreatic cancer in earlier stages improves one’s chance for survival, but University of Cincinnati researchers wanted to know if administering chemo before surgery in some patients, in addition to after, would make a difference.
Traditionally, pancreatic cancer is treated with surgery first and chemotherapy second. But Davendra Sohal, MD, associate professor of medical oncology at UC and medical oncologist with UC Health, was looking for ways to improve outcomes. So in a clinical trial, he and others enrolled 102 early-stage patients and administered chemotherapy before surgery and after. ....

Davendra Sohal , Uc Cancer Center , University Of Cincinnati , Uc Health , தவேந்திரா சோஹல் , அக் புற்றுநோய் மையம் , பல்கலைக்கழகம் ஆஃப் ஸிந்ஸந்யாடீ , அக் ஆரோக்கியம் ,

Study: pandemic's impact on lung cancer

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Study: pandemic’s impact on lung cancer
When the pandemic hit the U.S. in early 2020, many routine activities came to a halt.
The same occurred with doctors’ visits – regular checkups and screening for many health conditions.
A recent study led by University of Cincinnati Cancer Center researchers shows the impact the pandemic had on lung cancer screening, which experts say could be bad for both screening programs in general and for the overall well-being of patients. The article appears on the website of the Journal of the American College of Surgeons in advance of print.
Robert Van Haren, MD, assistant professor of surgery at UC, a UC Health thoracic surgeon and corresponding author on the study, says low-dose radiation CT scans have been shown to catch lung cancer earlier. He adds that lung cancer is the leading cause of cancer death in the U.S., but if it’s detected early, it has cure rates as high as 90%. UC created the first lung cancer ....

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