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Scientists develop new gene drive with a built-in genetic barrier

CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed to stop the transmission of devastating diseases such as malaria and dengue fever. ....

Anna Buchman , Omar Akbari , Emily Henderson , California Institute Of Technology , Nature Communications , University Of California San Diego , Innovative Genomics Institute , Uc San Diego Division Of Biological Sciences , California San Diego , Synthetic Postzygotic , Engineering Species , Diego Division , Biological Sciences , California Institute , Study Lead Author , California San , Dengue Fever , அண்ணா புச்மேன் , எமிலி ஹென்டர்சன் , கலிஃபோர்னியா நிறுவனம் ஆஃப் தொழில்நுட்பம் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா சான் டியாகோ , புதுமையானது மரபியல் நிறுவனம் , அக் சான் டியாகோ பிரிவு ஆஃப் உயிரியல் அறிவியல் , கலிஃபோர்னியா சான் டியாகோ , டியாகோ பிரிவு ,

Researchers Create New CRISPR Tools to Help Contain Mosquito Disease Transmission

Researchers Create New CRISPR Tools to Help Contain Mosquito Disease Transmission
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San Diego Division , United States , San Diego , University Of California San Diego , Norbert Perrimon , Xuechun Feng , Valentino Gantz , Enzo Mameli , Megan Lee , Alena Bishop , Nature Communications , National Emerging Infectious Diseases Laboratories , Uc San Diego Division Of Biological Sciences , National Institutes Of Health , Division Of Biological Sciences , Harvard Medical School , National Institute , West Nile , California San Diego , Biological Sciences , Del Amo , National Institutes , Tata Trusts , General Medical Sciences , சான் டியாகோ பிரிவு , ஒன்றுபட்டது மாநிலங்களில் ,

Synthetic SPECIES developed for use as a confinable gene drive

Scientists have developed a gene drive with a built-in genetic barrier that is designed to keep the drive under control. The researchers engineered synthetic fly species that, upon release in sufficient numbers, act as gene drives that can spread locally and be reversed if desired. ....

Anna Buchman , John Marshall , Omar Akbari , Michael Perry , Isaiah Shriner , Junru Liu , Igor Antoshechkin , Sciences Ph , California Institute Of Technology , Nature Communications , University Of California San Diego , Innovative Genomics Institute , Uc San Diego Division Of Biological Sciences , California San Diego , Synthetic Postzygotic , Engineering Species , Diego Division , Biological Sciences , California Institute , Ting Yang , Biological Sciences Phd , Biomedical Environmental Chemical Engineering , Cell Biology , Developmental Reproductive Biology , Gene Therapy , அண்ணா புச்மேன் ,

New CRISPR Tools Help Contain Mosquito Disease Transmission

New CRISPR Tools Help Contain Mosquito Disease Transmission
Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as
Anopheles and
Much less genetic engineering has been devoted to
Culex genus mosquitoes, which spread devastating afflictions stemming from West Nile virus the leading cause of mosquito-borne disease in the continental United States as well as other viruses such as the Japanese encephalitis virus (JEV) and the pathogen causing avian malaria, a threat to Hawaiian birds.
University of California San Diego scientists have now developed several genetic editing tools that help pave the way to an eventual gene drive designed to stop ....

San Diego Division , United States , San Diego , University Of California San Diego , Norbert Perrimon , Xuechun Feng , Valentino Gantz , Enzo Mameli , Megan Lee , Alena Bishop , Nature Communications , National Emerging Infectious Diseases Laboratories , Uc San Diego Division Of Biological Sciences , National Institutes Of Health , Division Of Biological Sciences , Harvard Medical School , National Institute , West Nile , California San Diego , Biological Sciences , Del Amo , National Institutes , Tata Trusts , General Medical Sciences , சான் டியாகோ பிரிவு , ஒன்றுபட்டது மாநிலங்களில் ,

New view of species interactions offers clues to preserve threatened ecosystems

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IMAGE: A blue magpie (Urocissa ornate), native to the rainforests of Sri Lanka, was photographed near the Sinharaja Forest Reserve, a World Heritage site that was part a new study of.
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Credit: Christopher Wills, UC San Diego
As the health of ecosystems in regions around the globe declines due to a variety of rising threats, scientists continue to seek clues to help prevent future collapses.
A new analysis by scientists from around the world, led by a researcher at the University of California San Diego, is furthering science s understanding of species interactions and how diversity contributes to the preservation of ecosystem health. ....

Puerto Rico , Sri Lanka , Xiankun Li , Shuai Fang , Chengjin Chu , Sisira Ediriweera , Jess Zimmermann , Xiangcheng Mi , Chang Fu Hsieh , Maria Uriarte , Heming Liu , Lillian Jennifer Rodriguez , Sheng Hsin Su , Yadvinder Malhi , Savi Gunatilleke , Jill Thompson , Raman Sukumar , David Kenfack , Yi Jin , Buhang Li , Xihua Wang , James Lutz , Zhanqing Hao , George Chuyong , Bonifacio Pasion , Sara Germain ,