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Sex hormones drive differences in male and female mouse kidneys

Female kidneys are known to be more resilient to disease and injury, but males need not despair. A new USC Stem Cell-led study published in Developmental Cell describes not only how sex hormones drive differences in male and female mouse kidneys, but also how lowering testosterone can "feminize" this organ and improve its resilience. ....

Ingileifb Hallgrimsdottir , Megan Rommelfanger , Junhyong Kim , Mandy Mcmahon , Megan Craig , Jin Guo , Zhen Miao , Adaml Maclean , Lingyun Ivy Xiong , Kari Koppitch , Jing Liu , Lior Pachter , National Institutes Of Health , University Of Pennsylvania , National Science Foundation , Keck School Of Medicine , California Institute Of Technology , Edythe Broad Center , Mcmahon Lab , Stem Cell Research , Developmental Cell , Regenerative Medicine , Keck School , National Institutes , Ifan Gao , California Institute ,